ID A0A1L7CYU4_9CORY Unreviewed; 647 AA.
AC A0A1L7CYU4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:APT90963.1};
GN ORFNames=CSPHI_07865 {ECO:0000313|EMBL:APT90963.1};
OS Corynebacterium sphenisci DSM 44792.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1437874 {ECO:0000313|EMBL:APT90963.1, ECO:0000313|Proteomes:UP000185469};
RN [1] {ECO:0000313|EMBL:APT90963.1, ECO:0000313|Proteomes:UP000185469}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44792 {ECO:0000313|EMBL:APT90963.1,
RC ECO:0000313|Proteomes:UP000185469};
RA Ruckert C., Albersmeier A., Winkler A., Kalinowski J.;
RT "Complete genome sequence of Corynebacterium sphenisci CECT 5990(T) (=DSM
RT 44792(T)), isolated from healthy wild penguins.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP009248; APT90963.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L7CYU4; -.
DR STRING; 1437874.CSPHI_07865; -.
DR KEGG; csph:CSPHI_07865; -.
DR Proteomes; UP000185469; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:APT90963.1};
KW Cell division {ECO:0000313|EMBL:APT90963.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185469};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..259
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 304..623
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 647 AA; 68502 MW; FED4BABCBD2C905E CRC64;
MRAAGGGARM ATTAADFARR RTWVQLVGLL IALAVVARLG WVQLIVGPEL SALAAQQRTV
TLVDPARRGA IEDRSGNALA FTMEARSITV HPNTLRSYIE DRHRLWPEDT EEPEPRMERI
AEELPGLIGV RDLDEIDRRT GGRRRVGDAA ERVEGAAAVP EGISSREILD KLRNEESTYE
VLVRNVDPDK AAAVVERFPE LVAERQDIRQ YPNGAVGANV IGKIGMDGVG QFGFEAARDA
TLQGVNGGRT VDIAANGIAI PGSTRDRVAP VDGTSYELTL DVDMQYQVQQ QLEQAVANSG
AAGGSAVVLD ARSGEVLTMA QSGTANPNKD IGVEVEQGRS IGNTAVTSPF EPGSVAKVIT
AAAAIEDGVT TPDEVHTVPG SIRMAGVEVS DAWQHGEERF TTTGIFGKSS NVGTLMLADR
VGQDRFARIL TAFGLGQPTG VELPGETAGL VPSRQQWSGG TFANLPIGQG MAMSLLQMTG
IYQTIANDGV RVPPRIIRAS TAPGGDRVEA PEPEGVTVVS PETARTVREM FEAVVQDDPT
GVQQGTGPQA AVPGYRIAGK TGTAQKVDED TGAYSNSRYY ITFAGIAPAD DPRFVIGIML
DEPVRGVHGE GGQSAAPLFH DIAAWALDRY NVPPSPPAEG RLLLDAG
//
