ID   A0A1L7F216_9PSEU        Unreviewed;       472 AA.
AC   A0A1L7F216;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=PhoH family protein {ECO:0000313|EMBL:APU18870.1};
GN   ORFNames=UA75_04195 {ECO:0000313|EMBL:APU18870.1};
OS   Actinoalloteichus sp. GBA129-24.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinoalloteichus.
OX   NCBI_TaxID=1612551 {ECO:0000313|EMBL:APU18870.1, ECO:0000313|Proteomes:UP000185506};
RN   [1] {ECO:0000313|EMBL:APU18870.1, ECO:0000313|Proteomes:UP000185506}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GBA129-24 {ECO:0000313|EMBL:APU18870.1,
RC   ECO:0000313|Proteomes:UP000185506};
RA   Ruckert C., Nouioui I., Willmese J., van Wezel G., Klenk H.-P.,
RA   Kalinowski J., Zotchev S.B.;
RT   "Complete genome sequence of Actinoalloteichus fjordicus DSM 46856
RT   (=GBA129-24).";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC       {ECO:0000256|ARBA:ARBA00038093}.
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DR   EMBL; CP016077; APU18870.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1L7F216; -.
DR   STRING; 1612551.UA75_04195; -.
DR   KEGG; acti:UA75_04195; -.
DR   OrthoDB; 9805148at2; -.
DR   Proteomes; UP000185506; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003714; PhoH.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR   Pfam; PF02562; PhoH; 1.
DR   Pfam; PF13638; PIN_4; 1.
DR   SMART; SM00670; PINc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT   DOMAIN          45..172
FT                   /note="PIN"
FT                   /evidence="ECO:0000259|SMART:SM00670"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   472 AA;  51324 MW;  0F3A52B49241BCBB CRC64;
     MTAPRSSRRS ASRTSSSVSN TPEVTAEPAR RATRARGTRT KDRTATYVLD TSVLLSDPWA
     ITRFAEHSVV LPLVVISELE GKRHHPELGW FAREALRLLD DLRLRHGRLD RPIPVGEADG
     TLHVELNHTD PTVLPPGFRT DSGDARILAC ALNLAAEGRR VTLVTKDMPL RVKAGSVGLV
     ADEYRAQNVA PSGWTGMADL DVEHELIDAL FKEGTVDLDE ARDMPCNTGL RLLSGTGSAL
     ARVTAEKRVR LVRGDREAFG LRGRSAEQRI ALDLLLDPEI GIVSLGGRAG TGKSALALCA
     GLESVLERSQ HRKVVVFRPV YAVGGQELGY LPGSESEKMQ PWAEAVFDTL GALAGQHVID
     EVVDRGMLEV LPLTHIRGRS LHDSFVIVDE AQSLERNVLL TVLSRLGSNS RVVLTHDVAQ
     RDNLRVGRHD GVAAVIEKLK GHPLFAHVTL TRSERSPIAA LVTEMLEGDS PL
//