ID   A0A1L7WVJ9_9HELO        Unreviewed;       359 AA.
AC   A0A1L7WVJ9;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN   ORFNames=PAC_06688 {ECO:0000313|EMBL:CZR56799.1};
OS   Phialocephala subalpina.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Mollisiaceae; Phialocephala;
OC   Phialocephala fortinii species complex.
OX   NCBI_TaxID=576137 {ECO:0000313|EMBL:CZR56799.1, ECO:0000313|Proteomes:UP000184330};
RN   [1] {ECO:0000313|EMBL:CZR56799.1, ECO:0000313|Proteomes:UP000184330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 11012 {ECO:0000313|EMBL:CZR56799.1,
RC   ECO:0000313|Proteomes:UP000184330};
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR   EMBL; FJOG01000008; CZR56799.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1L7WVJ9; -.
DR   STRING; 576137.A0A1L7WVJ9; -.
DR   OrthoDB; 4070889at2759; -.
DR   Proteomes; UP000184330; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184330};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..359
FT                   /note="Tyrosinase copper-binding domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012001622"
FT   DOMAIN          91..108
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          275..286
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   359 AA;  40500 MW;  70F6523756E4BCF7 CRC64;
     MHFSQVLSST LLLLTSATAA VAAPIEERTT CKDLAVRKEW RTLSEAERLE YIGAVKCLMS
     LPAQTGDFFA GAKTRYDDFL ALHINSTDYV HFNGPFLPWH RWLLKLWEDE LRNTCGYTGY
     QPWWDLLADN TIEGYPASPL FDDVYGMGGN GPYVEYVNDT SIFPVTTPTE IPGRTGGGCV
     ATGPFANLTI NMGMGLDLSY NPHCMRRDFS PLLVSEAFSD ANYAAALASE NFQELNLNIQ
     GYSFEISGMR LHAGLHIGVG GQVGDQADMW SSPGDPIFWF IHSSLDRLWN NWQRECWNER
     KTEIMGPDTM FAYPFNFFGD IPYTNITLDY ELEYEHFGSN VRIGDIMDVE ASNLCYTYE
//