ID   A0A1L7XCL7_9HELO        Unreviewed;       579 AA.
AC   A0A1L7XCL7;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Probable alcohol dehydrogenase {ECO:0000313|EMBL:CZR62779.1};
GN   ORFNames=PAC_12676 {ECO:0000313|EMBL:CZR62779.1};
OS   Phialocephala subalpina.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Mollisiaceae; Phialocephala;
OC   Phialocephala fortinii species complex.
OX   NCBI_TaxID=576137 {ECO:0000313|EMBL:CZR62779.1, ECO:0000313|Proteomes:UP000184330};
RN   [1] {ECO:0000313|EMBL:CZR62779.1, ECO:0000313|Proteomes:UP000184330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 11012 {ECO:0000313|EMBL:CZR62779.1,
RC   ECO:0000313|Proteomes:UP000184330};
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974,
CC         ECO:0000256|PIRSR:PIRSR000137-2};
CC   -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR   EMBL; FJOG01000021; CZR62779.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1L7XCL7; -.
DR   STRING; 576137.A0A1L7XCL7; -.
DR   OrthoDB; 3382025at2759; -.
DR   Proteomes; UP000184330; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR012132; GMC_OxRdtase.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00623; GMC_OXRED_1; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|RuleBase:RU003968};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184330}.
FT   DOMAIN          89..112
FT                   /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS00623"
FT   BINDING         91
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ   SEQUENCE   579 AA;  63508 MW;  00B3A72C117B9BC7 CRC64;
     MTVPTTKNFD FIVVGGGTAG NVVAGRLAEN PKVSVLVIEA GPGNPRQIPE ITTPARAFEL
     RDSNYDWAYK TTMIDRPDYT RVEKPNTRGK VLGGSSCLNY YTWVPGSAAT FNDWEAFGGS
     DWNWAGVEKY LKKPAKYFDD DNLYPAELKK VLASENGLLP ISHSDLVPEM APFRDALEKA
     WVSKGEKLTD DIYSGEMHGL VKCINSIHKG FRSSSYVFVE NKPNVTILSS THSKKLILEG
     TTVKGVEVIG PNGQELTFYA DREVIVSSGV FESPKLLLLS GIGPEEVLGE HGIKPVLKSA
     HVGKNLLDHP IVPHVFMLKD GLGLDDHLLR NGPAKAGAIA TYKKDRSGPL GSGLLELVGF
     PRIDERLQKS KDYLAAKSKN GGKDPFGPGG QPHFEIDFVP MFCDAFQWHI PTPPTGSWFT
     IIVDLLRPVS APGQVKLNSA NCLDQPNINL NFLADDLDVM ALREGVRFVD DILMNGEGMK
     DIIGSDYPWP MPRHSDAAMD KLVLERSQTG FHPCGTTRLS KSIEEGVVDS QLKVHGIKNL
     RVIDASVFPI IPDCRIQNAV YMVAEKGADL IKAEYSSLY
//