ID   A0A1L7XGX8_9HELO        Unreviewed;      1946 AA.
AC   A0A1L7XGX8;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Probable APC1-subunit of anaphase-promoting complex (Cyclosome) {ECO:0000313|EMBL:CZR64290.1};
GN   ORFNames=PAC_14188 {ECO:0000313|EMBL:CZR64290.1};
OS   Phialocephala subalpina.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Mollisiaceae; Phialocephala;
OC   Phialocephala fortinii species complex.
OX   NCBI_TaxID=576137 {ECO:0000313|EMBL:CZR64290.1, ECO:0000313|Proteomes:UP000184330};
RN   [1] {ECO:0000313|EMBL:CZR64290.1, ECO:0000313|Proteomes:UP000184330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 11012 {ECO:0000313|EMBL:CZR64290.1,
RC   ECO:0000313|Proteomes:UP000184330};
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the APC1 family.
CC       {ECO:0000256|ARBA:ARBA00010547}.
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DR   EMBL; FJOG01000026; CZR64290.1; -; Genomic_DNA.
DR   STRING; 576137.A0A1L7XGX8; -.
DR   OrthoDB; 180933at2759; -.
DR   Proteomes; UP000184330; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR024990; Apc1.
DR   InterPro; IPR048971; Apc1_3rd.
DR   InterPro; IPR046794; Apc1_MidN.
DR   InterPro; IPR049255; Apc1_N.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR   Pfam; PF12859; ANAPC1; 1.
DR   Pfam; PF21282; APC1_3rd; 1.
DR   Pfam; PF20518; Apc1_MidN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000184330};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          30..773
FT                   /note="Anaphase-promoting complex subunit 1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12859"
FT   DOMAIN          911..1033
FT                   /note="Anaphase-promoting complex subunit 1 middle"
FT                   /evidence="ECO:0000259|Pfam:PF20518"
FT   DOMAIN          1729..1808
FT                   /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF21282"
FT   REGION          315..402
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          786..812
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        315..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..382
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1946 AA;  215809 MW;  22F3C5D4C592B127 CRC64;
     MASVTSLGLH KPTGLQYAIQ ERLVPSDPPS DSYKWLNYCN EHADESFDDD ELLVTPRSVV
     WSRGGIFRKS YNFDLEGEEV TQALLTTFPS LGPLAAKEGT STPKQRVKER RETAVVVFLK
     TQAHVYFLSG TSHVIHLPFE VESASATPNG LIIQRKLKVD NLVAASFKFP QVPPNSFVSS
     QPQPWSAASS QQSTFSIADL GAPKQMTIPH STLKDMWDPP SLKNDSNWPR LFSLSDPLAE
     MGLVVTQSPK TENRRHRRSS TKINALDTAE EILHVSHRDE FSPKTSSNPL VLAITLNRET
     SMYTVWKFAY VEEGSTTTQK QRVPSGTMSR RRSSFVPGSG TGATTPLGNG QSLRESIGGN
     PQILSRKPAK NDESKDEIAD LVSSLDPDFE GSTIPRRKSR RVSSMLARAD LSASHERSAF
     SELVTGHQPS RRGESLGSQH VRNSIGTYAG ANGTSFAQPT QFNQSINSFL EAPVDDLLDE
     LRAGGDFEGF HNMGLDDEEF DALRQEIVLA NVCSVPAEHS NVRYSTQNVP AAAQCKIFTL
     TAPPSAADDK QGNTIVICIL DPDEKKLLVL TLYLKVHKSD LDLSHNPKTG ASSEKDVSVV
     SLGHVMRAKG VIDACRIDDG QVSRILVLTE TPDGYGELSL QAPWSVLMKV PLPGQFIISN
     TRNLSHNPMP RAKREGGFKR VLSQGPRALR GLRNTKPGGI VDLVDDEKKM HQLQLVLQPR
     NPHVRKILEV CRAVLPGSRG GEGVLVFWWN VMQWIRLESL QTVDTEWSAL AITMFCLALA
     LSPSKTQPHQ THAKKKSRGF LRSSSGAQSD SENWDLMQME ETSNGNPVPE WAANTGWKWL
     TEQLETDSPS LSADNAASIF QPSDDDNPSF IRKHVKLARD FTATRFGQDS ISGCLPTSGS
     KNIEVRKAAL ADVFVGLHLW NEEQKLDTTM ADALSAGIIS LSPILAQLSR WLGWDAWIQY
     YEFEDASLID LDYNNGKMLC SAHDIGTRLI KFPDSPIRHM IPETFECPAI YDWIQSCLNS
     RVLTPFMTLP QFVASRSESS RKNAQDLDQW NRLTPRTLLF EQFFSTMQPS WSDVQFVEAL
     SSAGADLLLL ETLPEAVLVP LQETIVQSQA EPPANWSKEL LALAPSHEAN LDVHVICNFA
     AEPETSGPFD GSAEVERQSI TRSIFKDDRR MNEAMNILNT SKPTIARVKP QPTWTESELL
     EAQKEHAQML AYRTLAIPSG RGLIYFSARV PLLTQKWHLP GFNLSCVMKP DNNTVGADKA
     SFTEEKIGWA FFHSGVSAGL SISRDAKGID TSWILYNKPV PDLNNRHAGF LLALGLNGHL
     KSLAKWVAFK YLTPKHTMTS IGLLLGLAAS YIGTMDNLIT RLLSVHVTRM LPPGAAELNL
     SPLTQTTGIM GIGLLYCNTQ HRRMSEIMVS EIEHIDHDVD EGEPLRNEGY RLAAGFALGF
     INLGKGSDLR GLHDMRLTER LLALAAGTKK VDLTHVLDKA TAAAVVAIAL IFMKSENQVL
     ARKIDVPDSL LQFDYIRPDI FLLRTLARHL IMWSKIDPSL AWIKSNLPEP YRHRSTLETI
     TSLTSVDLPF YDILTGLCFS IALRFAGSAS LPVRDLLIHY LDQFMRICRL EANTFDKKLT
     RNTIRNCQDL LGLSVATVMA GTGDLVTFRR LRSMHGRDDS ETPYGSHLAA HLAIGALFLG
     GGTYTFGTSN LAIAALLVAF YPIFPSSVQD NKSHLQAFRH FWVMAAEPRC LVARDIDTNQ
     PIPTSIIITL RNGTQTQRHT PCLLPELDQI RTVRTDSPEY WNIVLDLEKN QTHIASFKST
     QTIYVRRRPA HDATTSPFQA TLQALNDSNA NTPHALEWIF ELPAFASLTK AEKALVLPPD
     HGGAIGVHAG TAETVVDARL VLEHATLDSG KKDRLLGLRL LFEWVDQATS EGRDVQWIRR
     EAVDRLKART WMMASEEQMS GLHQWS
//