ID A0A1L7XH49_9HELO Unreviewed; 659 AA.
AC A0A1L7XH49;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE SubName: Full=Probable ADP-ribosylation factor-binding protein GGA1 {ECO:0000313|EMBL:CZR64360.1};
GN ORFNames=PAC_14258 {ECO:0000313|EMBL:CZR64360.1};
OS Phialocephala subalpina.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Mollisiaceae; Phialocephala;
OC Phialocephala fortinii species complex.
OX NCBI_TaxID=576137 {ECO:0000313|EMBL:CZR64360.1, ECO:0000313|Proteomes:UP000184330};
RN [1] {ECO:0000313|EMBL:CZR64360.1, ECO:0000313|Proteomes:UP000184330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11012 {ECO:0000313|EMBL:CZR64360.1,
RC ECO:0000313|Proteomes:UP000184330};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
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DR EMBL; FJOG01000026; CZR64360.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L7XH49; -.
DR STRING; 576137.A0A1L7XH49; -.
DR OrthoDB; 460229at2759; -.
DR Proteomes; UP000184330; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0016482; P:cytosolic transport; IEA:UniProt.
DR GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14235; GAT_GGA_fungi; 1.
DR CDD; cd16998; VHS_GGA_fungi; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.60.40.1230; -; 1.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR008153; GAE_dom.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR041198; GGA_N-GAT.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47180; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR PANTHER; PTHR47180:SF1; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF18308; GGA_N-GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50180; GAE; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000184330};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 32..168
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 195..322
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT DOMAIN 539..657
FT /note="GAE"
FT /evidence="ECO:0000259|PROSITE:PS50180"
FT REGION 354..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 659 AA; 71562 MW; FAE281D807C69AF5 CRC64;
MEAASARMAA RDRFGQMGDP GPSQLQRFIQ QACSPENFEP NLGVNLEIAD LINSKKGNAP
REAAVAIVNY INHRNPNVSL LAISLLDICV KNCGYPFHLQ ISTKEFLNEL VRRFPERPPI
RPTRVQMKIL EAIEEWRGTI CQTSRYKEDL GFIRDMHRLL SYKGYVFPEV RREDAAVLNP
SDNLRSAEEM EEEERAAQSA KLQELIRRGG PEDLQEANRL MKVMAGYDTR QKTDYRAKAA
EEVGKVQQKA RLLEERLEGF KPGDVMTDGD VYEELASALQ SAHPKIQKMC EEESDDHEAV
AKLLEINDSI HRTVERYKLM KKGDVDAAAK IAKGTLGTST GVGKNASNEL SLIDFDPPEA
ESSTNGSSSA AAPPSSSNDL EDDLLGLSMG ESYGQGGGIS LGFGSNTNLP GPALLSSTSE
HSTARGPTPT RSPAPPATST GPNYSAFSAF GTPPPAQQAA PQPTLFQQQQ ARQQAAPPAP
AADPFAALAS PIRSTTPQQP QKSIFDFSSH QPPAKTSTPA PPPAADDDEW AFESALPEGP
PSNNITVSDT SLNISLHVTR ESATPSIITM SLSFSNKTEQ AVSELEFKAA VTKGFTLKLQ
PQTGRRLQPH EQAGVKQIIH LHGAEEGKAG TVKLRWKVSY MVGMQPMNEQ GEISSLGIA
//
