ID   A0A1L7XJB2_9HELO        Unreviewed;       390 AA.
AC   A0A1L7XJB2;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Related to monophenol monooxygenase (Tyrosinase) {ECO:0000313|EMBL:CZR65057.1};
GN   ORFNames=PAC_14957 {ECO:0000313|EMBL:CZR65057.1};
OS   Phialocephala subalpina.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Mollisiaceae; Phialocephala;
OC   Phialocephala fortinii species complex.
OX   NCBI_TaxID=576137 {ECO:0000313|EMBL:CZR65057.1, ECO:0000313|Proteomes:UP000184330};
RN   [1] {ECO:0000313|EMBL:CZR65057.1, ECO:0000313|Proteomes:UP000184330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 11012 {ECO:0000313|EMBL:CZR65057.1,
RC   ECO:0000313|Proteomes:UP000184330};
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FJOG01000029; CZR65057.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1L7XJB2; -.
DR   STRING; 576137.A0A1L7XJB2; -.
DR   OrthoDB; 1767219at2759; -.
DR   Proteomes; UP000184330; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF141; N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Monooxygenase {ECO:0000313|EMBL:CZR65057.1};
KW   Oxidoreductase {ECO:0000313|EMBL:CZR65057.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184330};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..390
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009875288"
FT   DOMAIN          133..150
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          312..323
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   390 AA;  42632 MW;  231B97DEFDD9BF17 CRC64;
     MRLNVLALIW VAASLAAPAP VASLSDESNS TSTSSGITLD ELQSQANANI LASLDKRHED
     LTSRGQPSPC NRNTVAIRKE YGKLTSVEKI NYINAVKCLQ QKSPRTPLLA APGVRTRYDD
     FVATHINQTL QIHYTGNFLS WHRYYVWIYE KALREECGYT GYQPYWEWSK YVAAPQDNPM
     LDGSSTSLSG NGVFVPNRSD VILTSPGVAS LYLKPGLGGG CIYNGPFANY TVNLGPISSG
     TTGVDGGLGY NPRCLSRDIN PYTAARFLTW SDVLSIMSQT DIYNFQMNLQ GIPGIGIGAH
     GGGHYTVGNA NDPSFFVHHG QVDRVWTIWQ WLDPVNRTYA LAQTNTYLNS PPSANTTLND
     TVQLGFAGGA TKEIGELMSV VEGDFCYIYV
//