ID A0A1L7XJD4_9HELO Unreviewed; 508 AA.
AC A0A1L7XJD4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Zinc transporter {ECO:0000256|RuleBase:RU369017};
GN ORFNames=PAC_15049 {ECO:0000313|EMBL:CZR65149.1};
OS Phialocephala subalpina.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Mollisiaceae; Phialocephala;
OC Phialocephala fortinii species complex.
OX NCBI_TaxID=576137 {ECO:0000313|EMBL:CZR65149.1, ECO:0000313|Proteomes:UP000184330};
RN [1] {ECO:0000313|EMBL:CZR65149.1, ECO:0000313|Proteomes:UP000184330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11012 {ECO:0000313|EMBL:CZR65149.1,
RC ECO:0000313|Proteomes:UP000184330};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Functions as a zinc transporter.
CC {ECO:0000256|RuleBase:RU369017}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|RuleBase:RU369017}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU369017}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation diffusion facilitator (CDF)
CC transporter (TC 2.A.4) family. SLC30A subfamily.
CC {ECO:0000256|RuleBase:RU369017}.
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DR EMBL; FJOG01000029; CZR65149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L7XJD4; -.
DR STRING; 576137.A0A1L7XJD4; -.
DR OrthoDB; 2730679at2759; -.
DR Proteomes; UP000184330; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006882; P:intracellular zinc ion homeostasis; IEA:InterPro.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR InterPro; IPR045316; Msc2-like.
DR PANTHER; PTHR45755; -; 1.
DR PANTHER; PTHR45755:SF5; ZINC TRANSPORTER; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|RuleBase:RU369017};
KW Ion transport {ECO:0000256|RuleBase:RU369017};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369017};
KW Reference proteome {ECO:0000313|Proteomes:UP000184330};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369017};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369017}; Transport {ECO:0000256|RuleBase:RU369017}.
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 234..252
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 273..292
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 324..343
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 367..390
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 396..421
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..23
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 55327 MW; 23D8599E41A89D03 CRC64;
MASNLPIPAP PRTPTPPTPI PEEPEEGLGS NGGPRTMRTT ITFDPNALSP MRDVFPSRFG
GMASPMGSSA GSTPTLGSDG KMGPPPPPGG SRGPFNFQTQ AIKDSPAMAN SVCQNDQFTS
NPNDPYLPPS NPYLLGVKYK ATRANSNQNI GKRRGHRYKH SSVSAQHQIF LEPPPRAPLA
LPASLPIPTY KEAWTSRSKE QTTRIVWCVC HILVAGYVLY SAAGSLALTA LSHLIFFDAV
SAIICVVVDI LSNFEVWKRS SIRHPFGLER AEVLAGFAMS VFLIFMGFDL ISHNLKHVLE
GMGSHTPHHP HAHERVSPGS VDSAALLSII ATLISAIALK NHARIGKTMR FAMISNLPSV
LSNPSHFLTL SCSSIMLLLP LLTITMYLWL DRLLCAIIAI SMFVLGVKLA MTQGLMLLMS
YSGKDVGEVM REVKTDPCVT HVEEARFWQV HYGLCLACLK LRVKGDEGQL VRLRERINFL
VKNRLGGGYG KGSGVKWEVT VQMTLDKS
//
