ID   A0A1L7XS00_9HELO        Unreviewed;       446 AA.
AC   A0A1L7XS00;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=cellulase {ECO:0000256|ARBA:ARBA00012601};
DE            EC=3.2.1.4 {ECO:0000256|ARBA:ARBA00012601};
GN   ORFNames=PAC_17709 {ECO:0000313|EMBL:CZR67810.1};
OS   Phialocephala subalpina.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Mollisiaceae; Phialocephala;
OC   Phialocephala fortinii species complex.
OX   NCBI_TaxID=576137 {ECO:0000313|EMBL:CZR67810.1, ECO:0000313|Proteomes:UP000184330};
RN   [1] {ECO:0000313|EMBL:CZR67810.1, ECO:0000313|Proteomes:UP000184330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 11012 {ECO:0000313|EMBL:CZR67810.1,
RC   ECO:0000313|Proteomes:UP000184330};
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC         cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00000966};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
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DR   EMBL; FJOG01000047; CZR67810.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1L7XS00; -.
DR   STRING; 576137.A0A1L7XS00; -.
DR   OrthoDB; 1638835at2759; -.
DR   Proteomes; UP000184330; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR018087; Glyco_hydro_5_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR34142:SF5; CBM1 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR34142; ENDO-BETA-1,4-GLUCANASE A; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW   Hydrolase {ECO:0000256|RuleBase:RU361153};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184330};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..446
FT                   /note="cellulase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009875310"
FT   DOMAIN          52..276
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
SQ   SEQUENCE   446 AA;  45798 MW;  43D56218A6B81509 CRC64;
     MFFKSVSVLG MIPLALGKGM NIAGGDFGCA IDGTCPTGST QLPLSSLGGG DGLGQMQHFV
     SDDQMNIFRL PVSWQFLVNN QLGGTLDSTN FGKYDQLMQA CLGTGTYCAI DIHNFARWNN
     QIIGQSSGVT NGQFTSLWTQ LATKYASSTK VIFGLMNEPH DLDVPTWATT VQAAVTAIRN
     AGASSQMILM PGTNFASAGQ FVSSGSADAL LAITNPDGST TGLIYDLHKY LDVDNSGTHA
     ECTTDNIADA FQIAADYLRT NGRQALCFTD FCAQNAFLNA NSDVFLGYIA WAAGSFATSY
     VLSLTPSKSN GKFVDNALAS QCVVSPWLNA GTATVAASTV SRVATSTRTS TLANTVATNM
     VTSAPVSNAA ASTTSASGSG ISPSKVAAGA STLATSISNA TATAGTGNFS ASATATASQI
     VSTAGAGMRR YTGGLLAGSL FVALLL
//