ID A0A1L8EN89_XENLA Unreviewed; 474 AA.
AC A0A1L8EN89;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Growth arrest-specific protein 7 isoform X1 {ECO:0000313|RefSeq:XP_018094081.1};
GN Name=gas7.S {ECO:0000313|RefSeq:XP_018094081.1,
GN ECO:0000313|Xenbase:XB-GENE-17338697};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018094081.1};
RN [1] {ECO:0000313|RefSeq:XP_018094081.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018094081.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018094081.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_018094081.1; XM_018238592.2.
DR AlphaFoldDB; A0A1L8EN89; -.
DR STRING; 8355.A0A1L8EN89; -.
DR PaxDb; 8355-A0A1L8EN89; -.
DR GeneID; 108702857; -.
DR KEGG; xla:108702857; -.
DR AGR; Xenbase:XB-GENE-17338697; -.
DR CTD; 108702857; -.
DR Xenbase; XB-GENE-17338697; gas7.S.
DR OMA; PMHHGDH; -.
DR OrthoDB; 5491246at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10S.
DR Bgee; 108702857; Expressed in lung and 17 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07649; F-BAR_GAS7; 1.
DR CDD; cd11829; SH3_GAS7; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR037957; GAS7_F-BAR.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR23065:SF57; GROWTH ARREST-SPECIFIC PROTEIN 7; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF16623; WW_FCH_linker; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443}.
FT REGION 150..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 320..354
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 474 AA; 54462 MW; B02B8D21DCB6FAB1 CRC64;
MSGALCRTLY AFTGDQHQQG LKFEAGEVIK VVQALDGGWW EGEKDGLRGW FPASYVQILE
KPGMMNAQRI EDQTQVPLPQ GWQSYMSPQG CQYYVNTLTN ETTWERPNSS PVSLKSPIVK
KMSLPTVNGF HSSGSSVHQP ESGNMHIRKA SNEHQSPGSP SPTKKQSKET TITINCVTFP
HPDTMPEQQL LKPGEWSYCD YFWADKRDAQ GNNTVTGFED LLQKQLKGKQ MQKEMAEFIR
ERIRIEEEYA KNLAKLSQSP LACQEEGTLG EAWAQVKKSL ADEAEVHLKF SSKLQSEVEK
PLLNFRENFK KDMKKFDHHI SDLRKQLASR NAAVEKARKA LAERQKDLDV KTQQLEIKLS
NKTEEDIKKA RRKSTQAGDD LMRCMDLYNQ AQSKWFEEMV TTTLELERLE VERVEIIRQH
LCQYTQLRHE TDMFNQGTVE PVDQLLQKVD PGKDRELWVK EHKTGDIRPV DMEI
//
