ID A0A1L8ENB2_XENLA Unreviewed; 609 AA.
AC A0A1L8ENB2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Major facilitator superfamily domain-containing protein 6-like protein A isoform X1 {ECO:0000313|RefSeq:XP_041433743.1};
GN Name=mfsd6l.S {ECO:0000313|RefSeq:XP_041433743.1,
GN ECO:0000313|Xenbase:XB-GENE-5841523};
GN Synonyms=mfsd6l {ECO:0000313|RefSeq:XP_041433743.1}, mfsd6l-a
GN {ECO:0000313|RefSeq:XP_041433743.1}, mfsd6l-b
GN {ECO:0000313|RefSeq:XP_041433743.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_041433743.1};
RN [1] {ECO:0000313|RefSeq:XP_041433743.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_041433743.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_041433743.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC {ECO:0000256|ARBA:ARBA00005241}.
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DR RefSeq; NP_001087560.1; NM_001094091.1.
DR RefSeq; XP_018093026.1; XM_018237537.1.
DR RefSeq; XP_018093027.1; XM_018237538.1.
DR RefSeq; XP_041433743.1; XM_041577809.1.
DR AlphaFoldDB; A0A1L8ENB2; -.
DR STRING; 8355.A0A1L8ENB2; -.
DR PaxDb; 8355-A0A1L8ENB2; -.
DR GeneID; 447384; -.
DR KEGG; xla:447384; -.
DR AGR; Xenbase:XB-GENE-5841523; -.
DR CTD; 447384; -.
DR Xenbase; XB-GENE-5841523; mfsd6l.S.
DR OMA; YEYLDFA; -.
DR OrthoDB; 5406687at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10S.
DR Bgee; 447384; Expressed in oocyte and 19 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17479; MFS_MFSD6L; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR024989; MFS_assoc_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR16172:SF22; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE; 1.
DR PANTHER; PTHR16172; UNCHARACTERIZED; 1.
DR Pfam; PF12832; MFS_1_like; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 18..546
FT /note="Major facilitator superfamily associated"
FT /evidence="ECO:0000259|Pfam:PF12832"
SQ SEQUENCE 609 AA; 68314 MW; 307EE8A1125EE8DF CRC64;
MSSTKQWDIS KALTVATLFY FFHNVGKFCL MPFLTLYFRQ LGLGAPLVGI IFGFKHAVHL
LWAPLCSFLA KNHHKQRFFI MTSLLLSAGV GSLFAYYPPL DKNIVSLFCN TSMPWKEQLN
PPIDISVSVD ENLNTTYAAP TDHQTTTGAL NTLPSSVGKL ATDPAMTSLD LEITTHQRFT
DQFPVTSNTI LEHQTKNVLG SGKAQKVMSS KSAASNSKQR SSLNNHTSPY ATHPNVSHHP
SIHERKVRDI GIDFTDNSLD PQHKIFLIVL VLVIIWEILA APLEWIADDS LYEYLDFVDA
TDRHGKLWIW GYLGASMGSI FITFLVDNLN CFVIYDIPRV FFHFFCYGGF LIGTLFLSTL
YPIHVSKKTE HSNKTVKALG FLGSDGRIVL TALTVFLLGA VGSTTQNFLF WQMQDVGSSE
LYMGLSIAVG LLSELTLYFF RNKLLKIFTF KWMVALGLFS LGVQCLYYSF LWAPWSVLAI
QILNAFSSGV IWWAINSQVV DLASPGTERS LQLALRWLAY GCGSSTGSFA SGFIISRFSL
AVLYQACCIT LLLWIIIFLL VQPKLPNTKK INYSRLLAAD NSDMSDSDEE QDRDWLVTAM
KDENSNRNW
//
