ID   A0A1L8ENC8_XENLA        Unreviewed;       379 AA.
AC   A0A1L8ENC8;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Arf-GAP with dual PH domain-containing protein 2 isoform X3 {ECO:0000313|RefSeq:XP_018094105.1};
GN   Name=adap2.S {ECO:0000313|RefSeq:XP_018094105.1,
GN   ECO:0000313|Xenbase:XB-GENE-6487506};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018094105.1};
RN   [1] {ECO:0000313|RefSeq:XP_018094105.1}
RP   IDENTIFICATION.
RC   STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018094105.1};
RC   TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018094105.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_018094105.1; XM_018238616.2.
DR   AlphaFoldDB; A0A1L8ENC8; -.
DR   STRING; 8355.A0A1L8ENC8; -.
DR   PaxDb; 8355-A0A1L8ENC8; -.
DR   GeneID; 108702865; -.
DR   AGR; Xenbase:XB-GENE-6487506; -.
DR   CTD; 108702865; -.
DR   Xenbase; XB-GENE-6487506; adap2.S.
DR   OMA; MQREPFK; -.
DR   OrthoDB; 1022106at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 108702865; Expressed in spleen and 12 other cell types or tissues.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:1902936; F:phosphatidylinositol bisphosphate binding; IEA:InterPro.
DR   CDD; cd13252; PH1_ADAP; 1.
DR   CDD; cd01251; PH2_ADAP; 1.
DR   Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR037849; PH1_ADAP.
DR   InterPro; IPR037851; PH2_ADAP.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR46021; ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN; 1.
DR   PANTHER; PTHR46021:SF6; ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   Pfam; PF00169; PH; 2.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SMART; SM00233; PH; 2.
DR   SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS50115; ARFGAP; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186698}.
SQ   SEQUENCE   379 AA;  43949 MW;  B8FE7CBE3E300623 CRC64;
     MVNRERNNQL LETLKLPENS ECADCGLPDP DWASCKVGVF ICLQCSGVHR SFTESGKVKS
     IQLDNWEDER LVQFMIGNGN LKAKKKYEAF VPPFYYRPHA NDCIALKEQW IRAKYQREEF
     MSNKVTMHTT ADREGILYKR GRDRKGFQER RFVLSRSEGL LKYYTKDNGK GPKGIIPIQS
     LNVMFQGEKI GHQHGLEITY MKDGQTRNIF VYHDSAEEIV AWYNALREAR LHYLKTTYPQ
     ASEAELIPKI TRNYSKVGYM EKTGPKKKEA FKKRWFNLDS GGRKLLYYKN PLDAFEKGGI
     FIGSKERGYA VQEGLPQGLK GNNYDCGIII QTPAREFVLT CENVKEQREW LKALRGVVSQ
     PMTKEDIIEE ANFRRKRPK
//