ID   A0A1L8EQC8_XENLA        Unreviewed;       375 AA.
AC   A0A1L8EQC8;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Arf-GAP with dual PH domain-containing protein 1 {ECO:0000313|RefSeq:XP_041434747.1};
GN   Name=adap1.S {ECO:0000313|RefSeq:XP_041434747.1};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_041434747.1};
RN   [1] {ECO:0000313|RefSeq:XP_041434747.1}
RP   IDENTIFICATION.
RC   STRAIN=J_2021 {ECO:0000313|RefSeq:XP_041434747.1};
RC   TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_041434747.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_041434747.1; XM_041578813.1.
DR   AlphaFoldDB; A0A1L8EQC8; -.
DR   STRING; 8355.A0A1L8EQC8; -.
DR   PaxDb; 8355-A0A1L8EQC8; -.
DR   KEGG; xla:379710; -.
DR   OMA; EFIHVER; -.
DR   OrthoDB; 1022106at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:1902936; F:phosphatidylinositol bisphosphate binding; IEA:InterPro.
DR   CDD; cd08843; ArfGap_ADAP1; 1.
DR   CDD; cd13252; PH1_ADAP; 1.
DR   CDD; cd01251; PH2_ADAP; 1.
DR   Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR037849; PH1_ADAP.
DR   InterPro; IPR037851; PH2_ADAP.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR46021:SF5; ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46021; ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   Pfam; PF00169; PH; 2.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SMART; SM00233; PH; 2.
DR   SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS50115; ARFGAP; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186698}.
SQ   SEQUENCE   375 AA;  43501 MW;  2F8AA3AE49BE2408 CRC64;
     MAEERNKRAV TELAGRPGNT VCADCGAPDP DWASYTLGLF VCLSCSGIHR NIPQISRVKS
     VNLDPWDDVQ IEYMSCLGNK VAEAKYESKL PAFYYKPTSS DCQVLREQWI RAKYERKEFI
     LIEKQEPYSA GYREGLLWKR GRDNGQFLSR KFVLSEREGA LKYFNKNDAR EPKSVMKIEY
     INATFQPTKI GNPNGLQITY LKDNSTRNIF VYHEDGKEIV DWFNAIRAAR FHYLQVAYPL
     ARDIELVPQL TRNFLKEGFM EKTGPKHTEG FRKRWFILDG RRLMYFKDPL DAFAKGEVFI
     GSTENKYEVQ EGLASSTQGN HWQYGVTIVT PERRFLFACE TDTDRAEWMA AFRTVLSRPM
     LPQEYAVEAH FKHKP
//