ID A0A1L8ER18_XENLA Unreviewed; 526 AA.
AC A0A1L8ER18;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=E3 ubiquitin/ISG15 ligase TRIM25 {ECO:0000313|RefSeq:XP_018093374.1};
GN Name=LOC108702435 {ECO:0000313|RefSeq:XP_018093374.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018093374.1};
RN [1] {ECO:0000313|RefSeq:XP_018093374.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018093374.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018093374.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_018093374.1; XM_018237885.2.
DR AlphaFoldDB; A0A1L8ER18; -.
DR STRING; 8355.A0A1L8ER18; -.
DR PaxDb; 8355-A0A1L8ER18; -.
DR GeneID; 108702435; -.
DR KEGG; xla:108702435; -.
DR OMA; FSAYEET; -.
DR OrthoDB; 2939962at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10S.
DR Bgee; 108702435; Expressed in spleen and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd12891; SPRY_PRY_C-I_2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465:SF39; B BOX AND SPRY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Ligase {ECO:0000313|RefSeq:XP_018093374.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ SEQUENCE 526 AA; 59327 MW; 0DCE56A157F38B71 CRC64;
MAAAADLRDE LNCSVCLDIY TDPVMLQCGH NFCLSCIKSV VASQGNAGAY TCPECRVKFK
GRPAVYRNRK LSNIAGYFHS SQAEQYDSWI MCSYCHSPVP AVKTCLQCEA SLCESHLKKH
TRSPEHILFE PTTSLDSRKC PIHKELLKYY CLEHDTCICT SCCLVGEHRG HQVERLNETS
EKTKAKLASI LSKMTAGREE VVKNIQTLTE QMRDIQERSA RVADRITAFF GDLREHLQRI
ESQIQLERSL HQDEALRHIS KLIQQLEKKK ADLCENMRHL EEVCIATDPL TVLREGQLTC
HEEDVDDQKQ DVEILSAGDM DDTAISITLQ RNLHNLTDII SALKTKRGFS AYEETDVLFD
VGTAGNHISV SDNLKTAFYC VQSQSRPCSA NRFTSNQILS TRSFDGGQHY WEVESSQSRG
WSVGVAYPSL KRRGIDACLG LNEKSWCVCV SGKDLSAMFN SSTNTIDRHF QNGPIGIYLD
YDAGLLSFYK VHFPIRHLHT FTATFTEPLC AAFFIDKDER ITITSS
//
