ID A0A1L8EWB9_XENLA Unreviewed; 299 AA.
AC A0A1L8EWB9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Homeobox protein Hox-D13 {ECO:0000256|ARBA:ARBA00041102};
GN Name=hoxd13.L {ECO:0000313|RefSeq:XP_018091423.1,
GN ECO:0000313|Xenbase:XB-GENE-17339466};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018091423.1};
RN [1] {ECO:0000313|RefSeq:XP_018091423.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018091423.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018091423.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the Abd-B homeobox family.
CC {ECO:0000256|ARBA:ARBA00006317}.
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DR RefSeq; XP_018091423.1; XM_018235934.2.
DR AlphaFoldDB; A0A1L8EWB9; -.
DR STRING; 8355.A0A1L8EWB9; -.
DR PaxDb; 8355-A0A1L8EWB9; -.
DR GeneID; 108701383; -.
DR KEGG; xla:108701383; -.
DR AGR; Xenbase:XB-GENE-17339466; -.
DR CTD; 108701383; -.
DR Xenbase; XB-GENE-17339466; hoxd13.L.
DR OMA; GWGMEAL; -.
DR OrthoDB; 728401at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10L.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR022067; HoxA13_N.
DR PANTHER; PTHR45804:SF4; HOMEOBOX PROTEIN HOX-D13; 1.
DR PANTHER; PTHR45804; SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF12284; HoxA13_N; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 230..290
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 232..291
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 299 AA; 33100 MW; 49BF8DA4F1C75E50 CRC64;
MCKALSKRTQ WEMEGLRGGE GSSSNQCRNF LSSPSVFGSP SGRTVPGLAY SAPDRSSSSR
AEATKEGPAC PASTGPSGPS LGCGYHFGNG YYSCRMSHGV GLQQNPLKSS SHASLGSFPV
EKYMDVSGLA STSVPSNEVA SRAKEVSYFQ GYTNPYQHVP GYLDMVSTFS SGEPRHETYI
SMEGYQSWTL ANGWNGQVYC AKDQSQAPHF WKSSFPGDVA LNQADMCVYR RGRKKRVPYT
KLQLKELENE YAVNKFINKD KRRRISATTN LSERQVTIWF QNRRVKDKKI VSKIKDTIS
//
