ID A0A1L8EY81_XENLA Unreviewed; 286 AA.
AC A0A1L8EY81;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ras-related protein Rab-40C {ECO:0000313|RefSeq:XP_018091954.1};
GN Name=rab40c.L {ECO:0000313|RefSeq:XP_018091954.1,
GN ECO:0000313|RefSeq:XP_041433439.1,
GN ECO:0000313|Xenbase:XB-GENE-17333268};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|RefSeq:XP_018091954.1};
RN [1] {ECO:0000313|RefSeq:XP_018091954.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018091954.1,
RC ECO:0000313|RefSeq:XP_041433439.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018091954.1,
RC ECO:0000313|RefSeq:XP_041433439.1};
RG RefSeq;
RL Submitted (APR-2022) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR RefSeq; XP_018091954.1; XM_018236465.2.
DR RefSeq; XP_041433439.1; XM_041577505.1.
DR STRING; 8355.A0A1L8EY81; -.
DR PaxDb; 8355-A0A1L8EY81; -.
DR GeneID; 108701609; -.
DR KEGG; xla:108701609; -.
DR AGR; Xenbase:XB-GENE-17333268; -.
DR CTD; 108701609; -.
DR Xenbase; XB-GENE-17333268; rab40c.L.
DR OMA; PMRGRMG; -.
DR OrthoDB; 5386089at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000186698; Chromosome 9_10L.
DR Bgee; 108701609; Expressed in egg cell and 19 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd04121; Rab40; 1.
DR CDD; cd03742; SOCS_Rab40; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47980; LD44762P; 1.
DR PANTHER; PTHR47980:SF2; RAS-RELATED PROTEIN RAB-40C; 1.
DR Pfam; PF00071; Ras; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 175..228
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 245..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 31639 MW; 4EDCA1C2191A8745 CRC64;
MGTQGSPVKS YDYLLKFLLV GDSDVGKGEI LESLQDGASE SPYSYSNGID YKTTTILLDG
RRVKLELWDT SGQGRFCTIF RSYSRGAQGI LLVYDITNRW SFDGIDRWIK EIDEHAPGVP
RILVGNRLHL AFKRQVPTEQ ARSYAEKNGM TFFEVSPLCN FNVTESFTEL SRIVLMRHGM
EKIWRPNKVF SLQDLCCRAI VSCTPVHLID KLPLPVAIKS HLKSFSMANG MNAVMMHGRS
YSVAGSSGGA TGSGGGSKGN SLKRSKSIRP PQSPPQNCTR SNCKIS
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