ID A0A1L8F6B2_XENLA Unreviewed; 781 AA.
AC A0A1L8F6B2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=General transcription factor 3C polypeptide 4 {ECO:0000313|RefSeq:XP_018085032.1};
GN Name=gtf3c4.L {ECO:0000313|RefSeq:XP_018085032.1,
GN ECO:0000313|Xenbase:XB-GENE-6487708};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018085032.1};
RN [1] {ECO:0000313|RefSeq:XP_018085032.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018085032.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018085032.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_018085032.1; XM_018229543.2.
DR AlphaFoldDB; A0A1L8F6B2; -.
DR STRING; 8355.A0A1L8F6B2; -.
DR PaxDb; 8355-A0A1L8F6B2; -.
DR GeneID; 108698220; -.
DR KEGG; xla:108698220; -.
DR AGR; Xenbase:XB-GENE-6487708; -.
DR CTD; 108698220; -.
DR Xenbase; XB-GENE-6487708; gtf3c4.L.
DR OMA; WKPSHED; -.
DR OrthoDB; 5395638at2759; -.
DR Proteomes; UP000186698; Chromosome 8L.
DR Bgee; 108698220; Expressed in oocyte and 19 other cell types or tissues.
DR GO; GO:0000127; C:transcription factor TFIIIC complex; IEA:InterPro.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR GO; GO:0006384; P:transcription initiation at RNA polymerase III promoter; IEA:InterPro.
DR InterPro; IPR045803; DUF5921.
DR InterPro; IPR044230; GTF3C4.
DR InterPro; IPR024761; TFIIIC_delta_N.
DR InterPro; IPR024764; TFIIIC_Znf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR15496:SF2; GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4; 1.
DR PANTHER; PTHR15496; GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY; 1.
DR Pfam; PF19336; DUF5921; 1.
DR Pfam; PF12657; TFIIIC_delta; 1.
DR Pfam; PF12660; zf-TFIIIC; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 45..489
FT /note="Transcription factor IIIC 90kDa subunit N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12657"
FT DOMAIN 490..566
FT /note="DUF5921"
FT /evidence="ECO:0000259|Pfam:PF19336"
FT DOMAIN 698..748
FT /note="Transcription factor IIIC putative zinc-finger"
FT /evidence="ECO:0000259|Pfam:PF12660"
SQ SEQUENCE 781 AA; 88362 MW; DFABC311977351F7 CRC64;
MMAGEEKGTA AEDEEPSPSF RLTVTKREPA VKLLHSVTGV EPLAWSEDHR LSVCTGNSLC
LLELFCDLNG CAQELTLHRT CVSAPLTSCS LKVGKEKEVE DCREMFARSK QLTISQSFML
DRVFNPEGKF LPSFQRFKYA SWSPYGCDAN GRCLVAALTL DNRLTIHANV NRLHWRQLVD
LTEMYGQHLF EANYRVSGDE TPHADLDDFA EFKRRHSMQT PVRMEWSGIC ITQQVMENNE
CKDQSTVLLA VLFENGDIAV WQLQLPFLGK ESIASCNTIV SGISSPSVLA WWEYEHSNRK
MSGLIVGSRL GPIKILPVNL KAVKGYFTLR QPVILWQEAD QLPVHSIKCI ALYHPYQKCS
CSLIVAARGC YLFWCLLLIS KAGLNVHNSH VTGLHSLPII SMSVDKQNGT IYTCSVDGKV
QQLIPIFTDV ALKFEHQLIK LSDMFGPVKS HAITVSPCGA YLACITTEGI DNRIHPVTKT
YLVHFVALKS FEEAVAQLLE CSSQNLYHQM DLTDLVRWKI LKDKVIPQFL QEALDKKIEG
GSMYFWRFRL FLLRVWYQSL KKVTNELIWK PPSKEEKAAK LDDATVTNEK DDQKDAGPES
PTKETGENSP ADVTRDNPEA DCGTAEDGLL EIQEKIGAVE WHLVREHMKQ VLGEVYLHTR
ITENTSVPTR GICDYLTSKD SDDRAVQVII GHLENKMNKQ MFPEHCILCK EVLPFTDAKQ
ALCPNGHIWP RCFLTYQACQ SLLYRRCFLH DSIARHPAPG DPEWMKKLLN YPCILCDSPV
F
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