ID A0A1L8FG99_XENLA Unreviewed; 351 AA.
AC A0A1L8FG99;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=wnt4.S {ECO:0000313|RefSeq:XP_018083398.1,
GN ECO:0000313|Xenbase:XB-GENE-17330384};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018083398.1};
RN [1] {ECO:0000313|RefSeq:XP_018083398.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018083398.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018083398.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR RefSeq; XP_018083398.1; XM_018227909.2.
DR AlphaFoldDB; A0A1L8FG99; -.
DR STRING; 8355.A0A1L8FG99; -.
DR PaxDb; 8355-A0A1L8FG99; -.
DR GeneID; 108697659; -.
DR KEGG; xla:108697659; -.
DR AGR; Xenbase:XB-GENE-17330384; -.
DR CTD; 108697659; -.
DR Xenbase; XB-GENE-17330384; wnt4.S.
DR OMA; YRITRDC; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000186698; Chromosome 7S.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19336; Wnt_Wnt4; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR009142; Wnt4.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF101; PROTEIN WNT-4; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01844; WNT4PROTEIN.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 351 AA; 39113 MW; F702D32ACBD56130 CRC64;
MTPEYFLRSL LMMILAVFSA NASNWLYLAK LSSVGSISEE ETCEKLKGLI QRQVQMCKRN
LEVMDSVRRG AQLAIEECQY QFRNRRWNCS TLDTLPVFGK VVTQGTREAA FVYAISSAGV
AFAVTRACSS GDLEKCGCDR TVHGVSPQGF QWSGCSDNIA YGVAFSQSFV DVRERSKGGS
SSRALMNLHN NEAGRKAILN NMRVECKCHG VSGSCEVKTC WKAMPTFRKV GNVLKEKFDG
ATEAEQKKIG STKVLVPKNS QFKPHTDEDL VYLDSSPDFC DHDLKNGVLG TTGRQCNKTS
KAIDGCELMC CGRGFHTEEV EIVERCSCKF HWCCFVKCKQ CHKVVEMHTC R
//
