ID A0A1L8FIF7_XENLA Unreviewed; 234 AA.
AC A0A1L8FIF7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|RefSeq:XP_018080517.1};
GN Name=emg1.L {ECO:0000313|RefSeq:XP_018080517.1,
GN ECO:0000313|Xenbase:XB-GENE-6485598};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018080517.1};
RN [1] {ECO:0000313|RefSeq:XP_018080517.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018080517.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018080517.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase NEP1 family.
CC {ECO:0000256|ARBA:ARBA00008115}.
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DR RefSeq; XP_018080517.1; XM_018225028.2.
DR AlphaFoldDB; A0A1L8FIF7; -.
DR STRING; 8355.A0A1L8FIF7; -.
DR PaxDb; 8355-A0A1L8FIF7; -.
DR GeneID; 108696043; -.
DR KEGG; xla:108696043; -.
DR AGR; Xenbase:XB-GENE-6485598; -.
DR CTD; 108696043; -.
DR Xenbase; XB-GENE-6485598; emg1.L.
DR OMA; SAYTDDQ; -.
DR OrthoDB; 275493at2759; -.
DR Proteomes; UP000186698; Chromosome 7L.
DR Bgee; 108696043; Expressed in neurula embryo and 19 other cell types or tissues.
DR GO; GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0070475; P:rRNA base methylation; IEA:InterPro.
DR CDD; cd18088; Nep1-like; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR005304; Rbsml_bgen_MeTrfase_EMG1/NEP1.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR12636; NEP1/MRA1; 1.
DR PANTHER; PTHR12636:SF5; RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1; 1.
DR Pfam; PF03587; EMG1; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|RefSeq:XP_018080517.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW rRNA-binding {ECO:0000256|ARBA:ARBA00022730};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 234 AA; 25806 MW; 356E2EDFB4E6A56B CRC64;
MAASRESTLG KSTAGDEEQW GGPKAKRRRE KRLIVLLEGA CLETVRVGKT YELLNCDQHK
SLLIKNGRDP GQVRPDITHQ SLLMLLDSPL NRAGLLQVYI HTHRNVLIEV NPQTRIPRTF
PRFCGLMVQL LHKLSVRAAD GPQKLLKVIK NPLTDHLPVG CVKMALSFSG ESAPCVRDLV
PACEPVLFVV GAFAHGSVNV DYTERCVSIS QYPLSAALTC AKLCTAFEEV WGVQ
//
