ID A0A1L8FQF4_XENLA Unreviewed; 402 AA.
AC A0A1L8FQF4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=wnt9a.S {ECO:0000313|RefSeq:XP_041423260.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_041423260.1};
RN [1] {ECO:0000313|RefSeq:XP_041423260.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_041423260.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_041423260.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR RefSeq; XP_041423260.1; XM_041567326.1.
DR AlphaFoldDB; A0A1L8FQF4; -.
DR STRING; 8355.A0A1L8FQF4; -.
DR PaxDb; 8355-A0A1L8FQF4; -.
DR OMA; AGRKCHR; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000186698; Chromosome 6S.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19353; Wnt_Wnt9a; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR013303; Wnt9a.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF75; PROTEIN WNT-9A; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01894; WNT14PROTEIN.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 402 AA; 45105 MW; D52470B002615835 CRC64;
MLDGHLVLGW LSVALVALHC LGPAAANFGI PALMSLRSHT RLTSEGQSNG KSLHPPRSKE
EAPRHRRYTR TLTGNEPLTI LPLTSETEEA AVKAHYKICD RLKLERKQRR MCRRDPGVAE
TLIEAISMSA QECEYQFHFE RWNCTLEGRY RASLLKRGFK ETAFLYAISS AGLTHAMAKA
CSAGRMERCT CDEAPDLENR EAWQWGGCGD NLKYSNKFVK EFLANKSNKD LRARVDLHNT
NVGIKVIKAG VKTTCKCHGV SGSCTVRTCW RQLSPFHEIG KQLKQKYETS LKVGSTTNEA
TGEGDISPPK KPVAGHSDQI PRTTDLIYID DSPSFCRMSK YSPGTSGRRC YKDKNCESIC
CGRGHNTQSN VVTRPCQCQV RWCCYVECKE CTQKEEVYTC KD
//
