ID A0A1L8G152_XENLA Unreviewed; 1067 AA.
AC A0A1L8G152;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=ribosomal protein S6 kinase delta-1 {ECO:0000313|RefSeq:XP_018120484.1, ECO:0000313|RefSeq:XP_018120485.1};
GN Name=rps6kc1.S {ECO:0000313|RefSeq:XP_018120484.1,
GN ECO:0000313|RefSeq:XP_018120485.1,
GN ECO:0000313|Xenbase:XB-GENE-17337068};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|RefSeq:XP_018120484.1};
RN [1] {ECO:0000313|RefSeq:XP_018120484.1, ECO:0000313|RefSeq:XP_018120485.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018120484.1,
RC ECO:0000313|RefSeq:XP_018120485.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018120484.1,
RC ECO:0000313|RefSeq:XP_018120485.1};
RG RefSeq;
RL Submitted (APR-2022) to UniProtKB.
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DR RefSeq; XP_018120484.1; XM_018264995.2.
DR RefSeq; XP_018120485.1; XM_018264996.2.
DR STRING; 8355.A0A1L8G152; -.
DR PaxDb; 8355-A0A1L8G152; -.
DR GeneID; 108717713; -.
DR KEGG; xla:108717713; -.
DR AGR; Xenbase:XB-GENE-17337068; -.
DR CTD; 108717713; -.
DR Xenbase; XB-GENE-17337068; rps6kc1.S.
DR OMA; GKLWNYA; -.
DR OrthoDB; 5308056at2759; -.
DR Proteomes; UP000186698; Chromosome 5S.
DR Bgee; 108717713; Expressed in egg cell and 19 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd02677; MIT_SNX15; 1.
DR CDD; cd07287; PX_RPK118_like; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR042132; PX_S6K-delta-1.
DR PANTHER; PTHR15508; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR PANTHER; PTHR15508:SF2; RIBOSOMAL PROTEIN S6 KINASE DELTA-1; 1.
DR Pfam; PF04212; MIT; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00745; MIT; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF116846; MIT domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|RefSeq:XP_018120484.1,
KW ECO:0000313|RefSeq:XP_018120485.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transferase {ECO:0000313|RefSeq:XP_018120484.1,
KW ECO:0000313|RefSeq:XP_018120485.1}.
FT DOMAIN 1..132
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 787..1057
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 226..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1067 AA; 118351 MW; C09B6888E6DBCFD3 CRC64;
MMISQRDRGD LARFYTVTDP RRHQKGFTIY KVTARIVSRK NPEDVQEIVA WKRYSDFKKL
HIDLWQIHKN LFKQQELFPP FAKAKLFGRF DENVIEERRQ CAEDLLQFSA NIPALYNSSQ
LEDFFKGGEV HDGSDLIGPA EPTDFTDSLS DCSSDVRKDS CGPDDLTFTS VSECGGLSSD
SDLISLTVDK DSLSGIDDGM ASNQTSPSKF LGVLPSPESS IQSVFASSHE ATKSEGEKDR
QSSFPARLKQ KLSKPDYLTK AGSLITMAMK KESQEDYESA IEFYKKGVDL LLEGVQGEPS
PTRREAVKKK TAEYLMRAES ISSLCLKHSQ EELSAPPGAL SSRPSWNLRS PAEELKAFRV
LGVIDKVLLV LDTRTQETFI LKGLRKSEHC ATRKTIIPRL VPNMVRLQEY IISEESVFLV
LQHAEGGKLW NYLSKFFSRS ADESFDIPPS KSSHSDEDLL KHLAPCPKSS LDSRGSSDRN
MLSVQQLQSS LTISSQDDSS TQDEEGRESP LKWADSASSS DEECTTSYLT LCREYSQEKV
QPDTLSVEPL LGLDGQEDFP PDFVEQEPSC TTSNSLNSQL TSEEPLFIEE SGHSVPKPVL
MADALRKSRG SPMEFFRIDS RESNSDLGDH SSKAGTVDAY PSFQDDVDDD SEFEPERPSV
GTSVIITHDA ISRGSNDSFP VISFKDAALD DVCSIDEGRP DLLVNLPGTE QMDETEVVFQ
PNLLETDFME TKLLETPDVL LVNNSLEQLT GLNPNPLVAV EQTWGPHSQI TEQCQVNTNS
KESSRSASID PLESRGTLSD LDTLLPASVT FPLSYSTTTE GVSQVPCETS SGIKNVYDPQ
ETLALVSSEV SDELTTNLVQ LNIKIEDTDA CDVKKEFWGE KDIHKLFQEL DAKLSAASNF
IIPETFIQKW AAEIVLALDG LHGEGIVCRD LNPNNILLND GGHIQLTYFS RWSEVEDSCD
SDAIEKMYCA PEVGGITEET QACDWWSLGA LLFELLTIKA LVECHPAGMN THTTVSMPDY
VSKEAQSLVQ QLLQFNPLER LGAGVAGVDD IKSHPFFAGV KWEELAR
//
