ID A0A1L8G4F3_XENLA Unreviewed; 868 AA.
AC A0A1L8G4F3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Rho guanine nucleotide exchange factor 26 {ECO:0000313|RefSeq:XP_018121242.1};
GN Name=arhgef26.S {ECO:0000313|RefSeq:XP_018121242.1,
GN ECO:0000313|Xenbase:XB-GENE-6487358};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018121242.1};
RN [1] {ECO:0000313|RefSeq:XP_018121242.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018121242.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018121242.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_018121242.1; XM_018265753.2.
DR AlphaFoldDB; A0A1L8G4F3; -.
DR STRING; 8355.A0A1L8G4F3; -.
DR PaxDb; 8355-A0A1L8G4F3; -.
DR GeneID; 108718126; -.
DR KEGG; xla:108718126; -.
DR AGR; Xenbase:XB-GENE-6487358; -.
DR CTD; 108718126; -.
DR Xenbase; XB-GENE-6487358; arhgef26.S.
DR OMA; SQLSAXA; -.
DR OrthoDB; 12272at2759; -.
DR Proteomes; UP000186698; Chromosome 5S.
DR Bgee; 108718126; Expressed in egg cell and 18 other cell types or tissues.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd01221; PH_ephexin; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd11938; SH3_ARHGEF16_26; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035797; ARHGEF16/ARHGEF26_SH3.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR047271; Ephexin-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR047270; PH_ephexin.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12845; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR12845:SF4; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 26; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
SQ SEQUENCE 868 AA; 98816 MW; 3CDA4E601AF014BD CRC64;
MEECEVEFSH NDVKAIPLWR RMNPHQVEGL YNSLNPRPRP QSYQSPNGLL VTDFPVEDKH
TFTLTQPAER VTTSPDNRIS HKGGTSLYRP NGRILPSSSS MSLEYNSVAS NQRHLPQVVK
VVSSNSISFT ANGVLSSPSQ RTMLYNRTSN TITLTPDKEQ IVFGSSSPNG MVNCNNNNNP
MKAYDDRRET NTLCSDPLQG SPKTDANAKQ VLQRTPSNSS TLAETQSVVL STNSPAAFKS
GVQQIIPKGL ASEIKLTNKN NCQNSQNMGA SKRILKTRSL VEASSLPLVV AQEDGDKDSD
RDSPGTLRRG LRSTSYRRAV VSGLDFSNTT ERKKNNRMSQ PILRTVSEDK EKFSNLGRLK
RKILRGHGTF GSEENAVLYQ NYKEKALDID SDEDADSKEQ KEDRIIVEYK PLRSTWSQLS
VVRKNGLSQS LSQEERKRQE AMFEVISSEH SYLLSLEILI RMFKNSKQLS ATMTKTESHH
LFSNITDVYE ASKKFFRELE GRHQRNILIE DISDIVEKHA KSTFDPYVKY CTNEVYQQRT
LQRLIFTNAP FKEVLSKIES HEDCRNLPMI SFLILPMQRV TRLPLLMDTI CQKTPKDSAK
YEASKHALKE VGKLVRLCNE GARKMERMEM MVTINSQLEF KIKPFPLVSS SRWLLKRGEL
TGYVEDTGIF SKRTTKQQLY FFLFNDVLII TKKKSEESYN VTDYCLREKL LVEPYDNEEP
PSPVKNSTPI LYSRQSSANH LFTLTMLTNY AGEEVEILLG AETLSDRARW ITALVHSKDR
ANTDRTTLTQ VEITRTYTAK QPDELSLQVA DVVLVYQKVN DGWYEGERLR DGEKGWFLVE
CAKEITCRAT IEKNMERMGR LLALETNV
//
