ID A0A1L8G7T6_XENLA Unreviewed; 4827 AA.
AC A0A1L8G7T6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Baculoviral IAP repeat-containing protein 6 isoform X3 {ECO:0000313|RefSeq:XP_018118498.1};
GN Name=birc6.L {ECO:0000313|RefSeq:XP_018118498.1,
GN ECO:0000313|Xenbase:XB-GENE-6485640};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018118498.1};
RN [1] {ECO:0000313|RefSeq:XP_018118498.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018118498.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018118498.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_018118498.1; XM_018263009.2.
DR STRING; 8355.A0A1L8G7T6; -.
DR PaxDb; 8355-A0A1L8G7T6; -.
DR GeneID; 108716679; -.
DR AGR; Xenbase:XB-GENE-6485640; -.
DR CTD; 108716679; -.
DR Xenbase; XB-GENE-6485640; birc6.L.
DR OMA; LDAQCKL; -.
DR OrthoDB; 117123at2759; -.
DR Proteomes; UP000186698; Chromosome 5L.
DR Bgee; 108716679; Expressed in spleen and 19 other cell types or tissues.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0032465; P:regulation of cytokinesis; IEA:InterPro.
DR CDD; cd00022; BIR; 1.
DR CDD; cd00195; UBCc; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR001370; BIR_rpt.
DR InterPro; IPR022103; BIRC6.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR46116; (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME; 1.
DR PANTHER; PTHR46116:SF39; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6; 1.
DR Pfam; PF00653; BIR; 1.
DR Pfam; PF12356; BIRC6; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00238; BIR; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50143; BIR_REPEAT_2; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 420..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..841
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3895..3928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4233..4253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4424..4444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4806..4827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1585..1629
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2205..2239
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 421..445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4809..4827
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4827 AA; 528604 MW; E4E80567E3302D13 CRC64;
MAAGASEWLV LKDGCLRCDE HGVSSLSYHP SLNAILAVTN RGCIKVIDGT SGAILQSSAV
HVKPGGRVRC QYFPTVDKVI FVDDYAVGCR KDLNGILLLD TALQTPVSKA DDVIQLELPV
TEAQQLLSAC LKKIDVSSTE GYDLFIMQLK DGFKNTSHET AGNHKVAKWA TVTFHLPHHV
LKSLMGAIVN ELKKINQNIA ALPVASSVMD RLSYLLPSAR QELGVGPGRS VERSLMYSEA
NRRETFTSWP HVGYRWAQPD PMAQAGFYHQ PASSGDDRAM CFTCSVCLVC WEPTDEPWSE
HERHSPNCPF VKGEHTQNVP LSVTLATCPA QFPCADGTDR ISCFGVGNCP HFLAAATKRG
KICVWDVSKL MKVHLKFEVN AYDPAIVQLL ALSGDHNSAV EARRPTLVWL EDSSSCSDIP
KLEGDSDDLL DYSDSEERSR SDSVTGHTSQ KETLEMSLDI TAMSILQQPE KLQWEIVANV
LEDTVKDLEE LGANPSLASC KSEKTKEKHL EQHNIPFPCL LTGGLLTYRS PSSSPTSCNY
RRSLDALSRT PGESSSDQGS TDNESGTNSE LNSPLVKRTL PVLLLYSIKE SDEKAGKLFS
QMNNIMSKSL HDDGFTVPQI IEMELDNQEQ LLLQDPPVTY IQQFAEATAN LTSPDSDKWT
SMIPKPGTLV QCLRLPKFAE EENLCVDSII PCADGVHLLV GLQKCPAEQL SAINQVEALN
NLNKLNSALC SRRKVDVEPS VVNGTSINVI PCESSAEVHD PLIIQADKRT ASGGYLVIYK
MNYTTRIVTL EEDPVKFLHI KDPQDAITSL ILLQPDILDS REDDCEESSE ETPLTPKHVN
GKEKKCDMQS LGHLVVTTQS GYVKILDLST FEMMAKVDPP KKEGTDDVDP FASVVYCAGT
DRLCACTKGG ELHFLQIGEA CDDLDETDIL VDSSLSKGVE QLVEGVKPLS NPSSPGITGV
DLLVDQPFSL EMLTCLVELT RFETFIPRFS ATVPPCWVEV QQEQQQRRHP QHLHQHHHGD
AAQHTRTWKL QNDSTSWDEH VFELVLPKAC MVGHVDFKFL LNSNITNIPQ IQVTLLKNKT
PGLAKVHEAP VDRPVAFPLS PAFNVDIQKN GKHGLADLGE DLQNMDVEDS QSHRLCTFLE
DHKEDILCGP VWLASGLDLS GHAGMLTLTS PKLVKGMAGG KYRSFLIHVK AVNDRCTEDS
SNGATRPVVR IPAHKPQSVK GHSLATLLAK VVPGKEKSSA KLDTNNSTRK AKTLRGCDLL
QEVSVTIRRF KKTCIPKERV QRCAMLQFSE FHEKLLGTLC KKTEDGLATE HAQCLVLDIL
CWLAAVHSNG PGSLHEGKES LLSKTRNCLT EIVRACFFES GRSIAHKCSR FLALCISNGK
CDPSQQGFGC VLLKALLENI TYLPSAATGG SVYWYFVLLN YVKDEDLAGC STACASLLTA
ASRQLQDRLT PMEALLQTRY GLYSSPFDPV LFDLEVSGSS CKNIYSSSAS LQSDEIDLSE
VLLGSGKVNS CAAAEGSFTS LTGLLEVEPL HFTCVSTSDG TRIERDDAST FTVSTFGVTP
AVGGLSAGTV GEASTALSSA AQVALQSLSH AMASAEQQLQ VLQEKQQQLL KLQQQKAKLE
AKLHQTTAAA AAAASAVGPV HNSVPSNPVA APGFFIHPSD VIPPTPKTTP LFMTPPLTPP
NEAVSAVINA ELAQLFPGTV IDSPPAILPT HNKNTNKSRA NQLGSGLALA ISHASHFLQP
PPHQSIIIER MHSGARRFVT LDFGRPVLLT DILIPTCGDL ASLSIDIWSL GEEVDGRRLV
VATDISTHSL ILHDLIPPPV CRFMKITVIG RYGSTNARAK IPLGFYYGHT YILPWESELK
LMHDPLRGEN ESANQPDVDQ HLTMMVALQE DIQCRYNLAC HRLETLLQNI DLPPLNSANN
AQYFLRKPDK AVEEDSRVFS AYQDCIQLQL QLNLAHHAVQ RLKVALGMSR KTLQEQYDSK
ELIHTSSTEQ LRTIIRYLLD TLLSLLHSSN GHSVPGVLQN TFHAQACEEL FKHLCISGTP
KIRLHTGLLL VQLCGAERWW GQFLSNVLQE LYNSEQLLIF PQDRVFMLLS CIGQRSLSNS
GVLESLLNLL DSLLSPLQPH LPIYRRIEGV LDIPMISWVV MLVSRLLDYV ATVEDEAAAS
KKPLNGKERE RYVSGNQWSF INNSLHTHSM RSSTKGNSSL ERLYSRKIRK QLAHHKQQLN
LLKAKQKALV EQIEKEKIQS NKGSSYKLLV EQAKLKQATS KHFKDLIRLR RTAEWPRSAQ
DTEVSATKES PEIEPLPFTL AHERCISVVQ KLAQFLLSMD FTCHADLLLF VCKVLARIAN
ATRPTIHLGE IVNEQQLERL LLLLVGTDFN RGDISWGGAW AQYSLTCMLQ DILAGELLAP
LASDALDEVA MGEEAGASAG DSDDALQQLP LIEAVDEPLL PDISGAPPLS SLDKDKDIDL
ELLQDLMEVD IDPLDIDLEK DPLAAKVFKP ISSTWYDYWG ADYGTYNYNP YIGGVGIPVA
KPPATVEKNG TQTVTVSVSQ ALDARLEVGL EQQAELMLKM MSTLEADSIL QALTNSSPVL
SQPTSGTDDS LLRGMHVPNQ GNMLLVQSSS LPMLSACFNK LFSMLQVHHV QLESLLQLWL
TLSLNSNSSG GKENGADLFL YNANRVPVIP LNQASITSFL SVLSWHPNTL LRTWCLVLHS
LTLMTNMQLN SGSSSTIGPQ ENTAQLLVSD PNLLHVLVKF LSGTNPHGTN QHSPQVGPTA
TQAMQEFLTR LQVHLSSTSP QMFSEFLLKL IHILSTERGA LHTGQGPLDA QVKLLEFTLE
QNFEVVSVST ISAVIESVTF LVHHYITCSD KVVSRSGSDS SVGTRACFGG LFANIIRPGD
AKAVCGEMTR DQLMFDLLKL VNILVQLPLS SNKEFSARVP VVSSTTNSVS DEEKVYGGKD
CNSSASTTQN CTAYVADLVL ANQQIMSQIL SALGQCNSSA MAMIIGASGL HLTKHENFHG
GLDAISVGDG LFTILTTLSK KASTVQVMLQ PILTYMACGY MGRQGSLSTC QLSEPLLWFI
LRVLDTSEAL KAFHDMGGVQ LICNNMVTST RAIVNTARSM VSTIMKFLDS GPSKTTDSSL
KARVLASEPD NAEGIHNFAP LGTITSSSPT AQPAEVLLQA TPPHRRARSA AWSYIFLPEE
AWCDLTIHLP AAVLLKEIHI QPHLASLATC PSSVSVEISA DGVNMLPLST PVITSGLTYI
KIQLVKAEVA SAVCLRLHRP RDASTLGLSQ IKLLGLTAFG NTSSATVNNP FLPSEDQVSK
TSIGWLRLLH HCLTHISELE AMMASAAAPT ANLLQTCAAL LMSPYCGMHS PNIEAVLVKI
GLQSTRIGLR LIDILLRNCA ASGSDPADLN SPLLFGRLNG LSSDSTIDIL YQLGTTQDPG
TKDRIQALLK WVSDSAQVAS LKRSGWSNYI SPNSSTREFG LLMPSPSHLH CVAAILWHSY
ELPVEYDLPG LLNRDLFESL YKWSMSLPCN MVLKKAVDGL LCSMCHIHPN YFSLLMGWMG
ITPPPIQSQH RLSITDDSKK QDLNASLTDD SKNAQAPLAL TESHLATLAA ASQSPEAIKQ
LLDSGLPSLL VRSLVNFCFN HISSSDCAAT HTDFTQERLR RQHTSQHFSR MPVTANLVAP
ILRFLTEVGN CHVMKDWLGG TEVNPLWTAL LFLLCHSGAS TVTGPPHASS RCTLLNSNAG
NGLTTQQRTA VENATVAFFL QCISCHPNNQ RLMAQVLCEL FQSSPQRGSL PASANISGFI
RRLFLQLMLE DEKVTMFLQS PCPLYKGRIN ATSHIIQHPM YGAGHKFRTL NLPISTTLAE
LLDRVSDTPS ITAKLISEQK DDKEKKNQEE KEKVKAENGF QDNYSVVVAS GLKSQSKRAV
SSTPPRPPSR RGRVIADKVG SSSSGVESSS KTISIPVFHL YHKLLPGQPL PPEMTLAQLL
TLLYERKLPQ GFRSVDLTVK LGSKVISDPS LSKTDSFKRL HTEKEHGDLL GTCPEDEALS
PGDECVDSLL DDSYLETCPI QSPLQVFAGM GGLALIAERL PMLYPDVIQQ VSAPVVASTT
QEKPKDSDQF EWVTIEQSGE LVYEAPETIA AEPPPIKSAV QTMSPIPAHS LAAFGLFLRL
PGYAEVLLKE RKHAQCLLRL VLGVTDDGEG SHILQSPSAN VLPTLPFHVL RTLFSTMPLT
TDDGVLLRRM ALEIGAIHLI LACLSALSHH APRIPNSSTS QTEPQVSSTH SSGTCEEQQL
YWAKGTGFGT GSTASGWDVE QALTKQRLEE EHVTCLLLVL ASYINPAGCG INGEIQMNES
RGHNSNALPT VLLELLSQSC LIPAMSSYLR NDSVLDMARH VPLYRALLEL LRGIASCVAL
VPLLLPLTGG EEEEEQSESQ ASVGTLLAKM KTCVDTYTNR LRSKKDKAKA GVKPDASDPE
PEGLTLLVPD IQRTAEIVSA ATTSLRQANQ EKKLAEFSKK SSVKSKPFSI LRSLEEKYVA
IMKKLQFDTF EMVSEDDAGK LVFKMNYHYM SQVKNASDAN SAARARRLAQ EAVTLSTSLP
LSSSSSVFVR CDEERLDIMK VLITGPADTP YANGCFEFDV YFPQDYPNSP PLVNLETTGG
HSVRFNPNLY NDGKVCLSIL NTWHGRPEEK WNPQTSSFLQ VLVSIQSLIL VSEPYFNEPG
YERSRGTQGG TQSSREYDGN IRQATVKWAM LEQIRNASPC FKEVIHKHFY LKRAEIMAQC
EDWIVDIQQF SSDKRVGRTM SHHAAALKRH TAQLREELLK LLCPEGLDPD ADDSAEKCLA
AASCEETTLH DQAKPSSSKD TSSDFQF
//
