ID A0A1L8GAZ4_XENLA Unreviewed; 488 AA.
AC A0A1L8GAZ4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Thiamine transporter 2 {ECO:0000313|RefSeq:XP_018119422.1};
GN Name=slc19a3.2.L {ECO:0000313|RefSeq:XP_018119422.1,
GN ECO:0000313|Xenbase:XB-GENE-17331350};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018119422.1};
RN [1] {ECO:0000313|RefSeq:XP_018119422.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018119422.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018119422.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|PIRNR:PIRNR028739}; Multi-
CC pass membrane protein {ECO:0000256|PIRNR:PIRNR028739}.
CC -!- SIMILARITY: Belongs to the reduced folate carrier (RFC) transporter (TC
CC 2.A.48) family. {ECO:0000256|ARBA:ARBA00005773,
CC ECO:0000256|PIRNR:PIRNR028739}.
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DR RefSeq; XP_018119422.1; XM_018263933.2.
DR AlphaFoldDB; A0A1L8GAZ4; -.
DR PaxDb; 8355-A0A1L8GAZ4; -.
DR GeneID; 108717123; -.
DR KEGG; xla:108717123; -.
DR AGR; Xenbase:XB-GENE-17331350; -.
DR CTD; 108717123; -.
DR Xenbase; XB-GENE-17331350; slc19a3.2.L.
DR OMA; YHAEILL; -.
DR OrthoDB; 51626at2759; -.
DR Proteomes; UP000186698; Chromosome 5L.
DR Bgee; 108717123; Expressed in neurula embryo and 1 other cell type or tissue.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0090482; F:vitamin transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002666; Folate_carrier.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00806; rfc; 1.
DR PANTHER; PTHR10686; FOLATE TRANSPORTER; 1.
DR PANTHER; PTHR10686:SF37; THIAMINE TRANSPORTER 2; 1.
DR Pfam; PF01770; Folate_carrier; 1.
DR PIRSF; PIRSF028739; Folate_carrier; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR028739};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transport {ECO:0000256|PIRNR:PIRNR028739}.
SQ SEQUENCE 488 AA; 54881 MW; 0B224FDA50B90359 CRC64;
MAVCGKEYTN GWKYPTVLLC LFGFCANMKA LDPFTAQYFT GSYHNLTVEQ VKNSVLPVWT
YSYMALLIPV FLLTDYLRYK PVIFLQGLGL SISLLLMLIT HGVQAMQLAE FTYAIFSSCD
VAYYSYIYSM VDIVYYQRVT SYCRSITLVA AMLGAMLEQT LMTFAGVSYI SLNILTLTLA
LLSLVCSLFL PVPSRSMFFH KKMPGDTMLS KETGLPETQR QTEDTTMLME TEKASRTNVF
NVFWLLCKEV KECYTSNHIL YWSLWWALAT PIYNLLVNYS QLLWVYVEPS GRINAYNSGV
DAVSTFLGAI LSLSVGYVKV NCELFGEAVL TCLSIVDAGV LFFMSFSRSV WISYAGYIIF
KSSYMLFITI ATFNIAVNLS MERYALLFGF NTLVALVLQT ILTLFANHSG LGLDITSQFL
VYGSYFAVTA LIFMLWTTYL IASHYCKNPD NDLHSTIKAM SPQGYGLNSP TAGSVDPDNV
SHKHSFTQ
//
