ID A0A1L8GBD3_XENLA Unreviewed; 328 AA.
AC A0A1L8GBD3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Forkhead box protein L2 {ECO:0000256|ARBA:ARBA00034872};
GN Name=foxl2.L {ECO:0000313|RefSeq:XP_018119418.1,
GN ECO:0000313|Xenbase:XB-GENE-17346692};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018119418.1};
RN [1] {ECO:0000313|RefSeq:XP_018119418.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018119418.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018119418.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_018119418.1; XM_018263929.2.
DR AlphaFoldDB; A0A1L8GBD3; -.
DR STRING; 8355.A0A1L8GBD3; -.
DR PaxDb; 8355-A0A1L8GBD3; -.
DR GeneID; 108717121; -.
DR KEGG; xla:108717121; -.
DR AGR; Xenbase:XB-GENE-17346692; -.
DR CTD; 108717121; -.
DR Xenbase; XB-GENE-17346692; foxl2.L.
DR OMA; CSYWEHE; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000186698; Chromosome 5L.
DR Bgee; 108717121; Expressed in neurula embryo and 5 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20028; FH_FOXL2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047515; FH_FOXL2.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF342; FORKHEAD BOX PROTEIN L2; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 72..166
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 72..166
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
SQ SEQUENCE 328 AA; 36958 MW; DE32803DF29E8358 CRC64;
MRSSCAPTHY CSPGCYCLNQ GSDRMASFQT PEQGTVALMT HNSNGNKETE RGKEELQQQQ
EKGQEKPDPS QKPPYSYVAL IAMAIRESQE KRLTLSAIYQ YIISKFPFYE KNKKGWQNSI
RHNLSLNECF IKVPREGGGE RKGNYWTLDP ACEDMFEKGN YRRRRRMKRP FRPPPTHFQA
GKSLFGSDTY GYLSPPKYLQ STFMNNSWPL SQPPAPMSYT SCQMAGGNVS PVNVKGLSAS
SSYSPYSRVQ SMSLPSMVNS YNGMSHHHHP HAHHAQQLSP ASPAPAPPAP PNGVQFTCAR
QPPDLSMMHC SYWDHDAKHS ALHPRIDL
//
