ID A0A1L8GBM5_XENLA Unreviewed; 607 AA.
AC A0A1L8GBM5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Syndecan {ECO:0000256|RuleBase:RU000649};
GN Name=sdc1.L {ECO:0000313|RefSeq:XP_018119533.1,
GN ECO:0000313|Xenbase:XB-GENE-6251594};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018119533.1};
RN [1] {ECO:0000313|RefSeq:XP_018119533.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018119533.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018119533.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Cell surface proteoglycan. {ECO:0000256|RuleBase:RU000649}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU000649}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU000649}.
CC Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
CC -!- SIMILARITY: Belongs to the syndecan proteoglycan family.
CC {ECO:0000256|ARBA:ARBA00005343, ECO:0000256|RuleBase:RU000649}.
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DR RefSeq; XP_018119533.1; XM_018264044.2.
DR AlphaFoldDB; A0A1L8GBM5; -.
DR STRING; 8355.A0A1L8GBM5; -.
DR PaxDb; 8355-A0A1L8GBM5; -.
DR GeneID; 398348; -.
DR KEGG; xla:398348; -.
DR AGR; Xenbase:XB-GENE-6251594; -.
DR CTD; 398348; -.
DR Xenbase; XB-GENE-6251594; sdc1.L.
DR OMA; FVNREVI; -.
DR OrthoDB; 5360052at2759; -.
DR Proteomes; UP000186698; Chromosome 5L.
DR Bgee; 398348; Expressed in egg cell and 19 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR003585; Neurexin-like.
DR InterPro; IPR001050; Syndecan.
DR InterPro; IPR027789; Syndecan/Neurexin_dom.
DR InterPro; IPR030479; Syndecan_CS.
DR PANTHER; PTHR10915; SYNDECAN; 1.
DR PANTHER; PTHR10915:SF5; SYNDECAN-1; 1.
DR Pfam; PF01034; Syndecan; 1.
DR SMART; SM00294; 4.1m; 1.
DR PROSITE; PS00964; SYNDECAN; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180,
KW ECO:0000256|RuleBase:RU000649};
KW Heparan sulfate {ECO:0000256|ARBA:ARBA00023207,
KW ECO:0000256|RuleBase:RU000649}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Proteoglycan {ECO:0000256|ARBA:ARBA00022974,
KW ECO:0000256|RuleBase:RU000649};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000649};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 573..591
FT /note="Neurexin/syndecan/glycophorin C"
FT /evidence="ECO:0000259|SMART:SM00294"
SQ SEQUENCE 607 AA; 66576 MW; 069610C2E30134A5 CRC64;
MDKLLAALCL LGMCCSLAVT DVSVRSSPLD LEASGDDEDF SGSGIDDLDV DHVVPSTSAL
PSVLSAVPNF VQENTSPNAK VDEKDTAAEH TTRVVETTKP SEDPVEELVE PVFVGVGHDA
ESTSPEATTH KPTTHRPTTV KSTAGPMESI TEQNHHPHHH HHHHHHHHQN HTTTAKPTSA
TDQHVDNSDS PSGEDKSYIH HKVTTTSPID NEEPDLHEAD HRLTTIKPRN TEELINHHVP
DQDSPSGSSS TPYMEFEETT EDPSGARVHN VLIGHDEKTT TKPSENEEGD GMFAGHHEKP
TTTSPSNEEG SHIQHDTTTS SPSHHAEPDV EVHHSTTPAD MNKHHHHHHH HPHHHTTPEA
ITSVDEEIPH HVGDSTTPSD LNKHHHHHHP HHHTTSETTT SVDEVPHHVD DSTTPSDLNK
HHHHHHPHHH TTPETTKTTT SQTKHSAEVS TVVHKGRMAH GASATSAVPA LDDLVDLTTS
VVLEEGDSDP ADSKEDESSG EKEEDNFFFV NREVIQKGTA PPIHRMINND VSDNESTSDA
SHGIMERKEV LAGIIAGGVA GLAFAVFLVG FMLYRMKKKD EGSYSLEEPK QSNGGYQKPR
AQREFYA
//
