ID A0A1L8GGF1_XENLA Unreviewed; 246 AA.
AC A0A1L8GGF1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Tumor necrosis factor ligand superfamily member 6 {ECO:0000313|RefSeq:XP_018115349.1};
GN Name=faslg.S {ECO:0000313|RefSeq:XP_018115349.1,
GN ECO:0000313|Xenbase:XB-GENE-17337744};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018115349.1};
RN [1] {ECO:0000313|RefSeq:XP_018115349.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018115349.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018115349.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tumor necrosis factor family.
CC {ECO:0000256|ARBA:ARBA00008670}.
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DR RefSeq; XP_018115349.1; XM_018259860.2.
DR AlphaFoldDB; A0A1L8GGF1; -.
DR STRING; 8355.A0A1L8GGF1; -.
DR PaxDb; 8355-A0A1L8GGF1; -.
DR GeneID; 108715004; -.
DR KEGG; xla:108715004; -.
DR AGR; Xenbase:XB-GENE-17337744; -.
DR CTD; 108715004; -.
DR Xenbase; XB-GENE-17337744; faslg.S.
DR OMA; MACTVNF; -.
DR OrthoDB; 5347330at2759; -.
DR Proteomes; UP000186698; Chromosome 4S.
DR Bgee; 108715004; Expressed in spleen and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00184; TNF; 1.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR006053; TNF.
DR InterPro; IPR006052; TNF_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR11471; TUMOR NECROSIS FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11471:SF33; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6; 1.
DR Pfam; PF00229; TNF; 1.
DR PRINTS; PR01234; TNECROSISFCT.
DR SMART; SM00207; TNF; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50049; TNF_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 112..246
FT /note="TNF family profile"
FT /evidence="ECO:0000259|PROSITE:PS50049"
SQ SEQUENCE 246 AA; 28572 MW; EBD86A3418FB8950 CRC64;
MQQDMRYPQP SVFWMDPSRN PPLPSQVNMP LPPPFPDFRR KRRKNSTCTY LLIMFLLVVL
ALFGVGLGTY KIIELQRQLD NIKEISGDKG PALEKLVGLT KHPFEKKESR LAAHVTGKEG
KKLPLEWEET FGRAFTSGIQ YKNQSLVVNQ TGLYFLYSSI YFRNTSCQSK ELSHTVYKRS
QRYPAELTLM QNTEYQYCTS NNKWGRHSYL GALFNLTTDE MLYVNVSDVE LVSFDESRTY
FGLYKL
//
