ID A0A1L8GL47_XENLA Unreviewed; 614 AA.
AC A0A1L8GL47;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Kelch-like protein 36 {ECO:0000256|ARBA:ARBA00019802};
GN Name=klhl36.L {ECO:0000313|RefSeq:XP_018113446.1,
GN ECO:0000313|RefSeq:XP_041446123.1, ECO:0000313|RefSeq:XP_041446124.1,
GN ECO:0000313|RefSeq:XP_041446125.1,
GN ECO:0000313|Xenbase:XB-GENE-6486447};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_041446125.1};
RN [1] {ECO:0000313|RefSeq:XP_018113446.1, ECO:0000313|RefSeq:XP_041446123.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018113446.1,
RC ECO:0000313|RefSeq:XP_041446123.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018113446.1,
RC ECO:0000313|RefSeq:XP_041446123.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Probable substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex which mediates the ubiquitination and subsequent
CC proteasomal degradation of target proteins.
CC {ECO:0000256|ARBA:ARBA00003098}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_018113446.1; XM_018257957.2.
DR RefSeq; XP_018113447.1; XM_018257958.1.
DR RefSeq; XP_041446123.1; XM_041590189.1.
DR RefSeq; XP_041446124.1; XM_041590190.1.
DR RefSeq; XP_041446125.1; XM_041590191.1.
DR STRING; 8355.A0A1L8GL47; -.
DR PaxDb; 8355-A0A1L8GL47; -.
DR GeneID; 108714076; -.
DR KEGG; xla:108714076; -.
DR AGR; Xenbase:XB-GENE-6486447; -.
DR CTD; 108714076; -.
DR Xenbase; XB-GENE-6486447; klhl36.L.
DR OMA; GQVQHES; -.
DR OrthoDB; 5472491at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000186698; Chromosome 4L.
DR Bgee; 108714076; Expressed in neurula embryo and 16 other cell types or tissues.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18475; BACK_KLHL36; 1.
DR CDD; cd18266; BTB_POZ_KLHL36; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF4; KELCH-LIKE PROTEIN 36; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 45..112
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 614 AA; 69988 MW; 10DAEE063F99F173 CRC64;
MEGSRQTRVS WPHKISESSK LYRWEDHSTH VLHAFNEQRQ KGLFCDVVLV ADEQRVPAHR
NLLAACSDYF NSMFTIGMRE AHQKEVELVG ASYLGLKAVI DFLYNCDLSL DGGNIDYVLE
TAHLLQIWKV VDFCCEYLEN EVSEENYLYL QELASIYSLE RLGSYIDSFI RQNYATLSFT
ADFLQNISTQ KICQYLSSNQ IQHVGEHDLL QSALQWLTHS PERDNLGYQV LQNIRFQLIP
KSDLLHRVKP AVCSLLPKEA NCESLVEEAV YYHNNVSVQP LLQNTRSSLR AGVERLLFVG
GEVSEHCLEL SDDVCSLDMT KVQWLSETQL PARRSHHCVT VLGNFIFVAG GSFSRDNGGD
AASNLLYRYD PRWNQWIKVA SMNQRRVDFY LAAVSDRLVA VGGRNESGAL SSVESYCPQQ
DTWTYVSELP RFTYGHAGTV HKEFIYISGG HDYQIGPYRK NLLCYDHRAD AWEERRPMIT
ARGWHSMCTL EDSIYSVGGS DDNLESMERF DILSVECYSP QCNQWTRIAP LLQPNSESGV
AVLDGKIYIL GGYSWENTAF SRTVQVYDKE RQKWVKGTDL PKVIAGVSAC VCILKTGTDE
SKRTKTKRHS DRGR
//
