ID A0A1L8GT31_XENLA Unreviewed; 426 AA.
AC A0A1L8GT31;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Bone morphogenetic protein 7-like {ECO:0000313|RefSeq:XP_018110976.1, ECO:0000313|RefSeq:XP_018110977.1};
GN Name=bmp7.2.S {ECO:0000313|RefSeq:XP_018110976.1,
GN ECO:0000313|RefSeq:XP_018110977.1, ECO:0000313|RefSeq:XP_018110978.1,
GN ECO:0000313|Xenbase:XB-GENE-17339872};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|RefSeq:XP_018110977.1};
RN [1] {ECO:0000313|RefSeq:XP_018110976.1, ECO:0000313|RefSeq:XP_018110977.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018110976.1,
RC ECO:0000313|RefSeq:XP_018110977.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018110976.1,
RC ECO:0000313|RefSeq:XP_018110977.1};
RG RefSeq;
RL Submitted (APR-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR RefSeq; XP_018110976.1; XM_018255487.2.
DR RefSeq; XP_018110977.1; XM_018255488.2.
DR RefSeq; XP_018110978.1; XM_018255489.2.
DR STRING; 8355.A0A1L8GT31; -.
DR PaxDb; 8355-A0A1L8GT31; -.
DR GeneID; 108712945; -.
DR KEGG; xla:108712945; -.
DR AGR; Xenbase:XB-GENE-17339872; -.
DR CTD; 108712945; -.
DR Xenbase; XB-GENE-17339872; bmp7.2.S.
DR OMA; RIASKDM; -.
DR OrthoDB; 2912454at2759; -.
DR Proteomes; UP000186698; Chromosome 3S.
DR Bgee; 108712945; Expressed in blastula and 5 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19397; TGF_beta_BMP7; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF135; BONE MORPHOGENETIC PROTEIN 7; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..426
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041160925"
FT DOMAIN 316..426
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 426 AA; 49080 MW; 74458B49BFE3C2B7 CRC64;
MNALIVKRRL PLLLFLFNIS LSSISSNTIL ENDFHSSFAQ RRLKGHERRE IQKEILTILG
LQHRPRPYLP EKEKSAPLFM MDLYNAANIE EMNAEDASYL KKPISLNEAS SLASDQENGF
LAHADTVMSF ANLVDNDKEE YKNSYCQKFK FDLTDIPLGD ELTAAEFRIY KDYVQNNETY
QVTVYQMLQK HPNKDPYLFQ VDSRTIWGTE KGWLTFDITV TSNHWVINPH YNLGLQLSVE
SMDMQSVDLR LVGLDGRIGL QDKQPFMVAF FKTSEIHLRS IRSISNKHWN QERAKTYKEQ
DHFPPANITD GIMPTGKRRF SKQACKKHEL FVSFRDLGWQ DWIIAPEGYA AYYCDGECSF
PLNSFMNATN HAIVQTLVHF INPETVPKPC CAPTQLNGIS VLYFDDSSNV ILKKYKNMVV
EACGCH
//
