ID A0A1L8H0R1_XENLA Unreviewed; 600 AA.
AC A0A1L8H0R1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=RNA polymerase II elongation factor ELL3 {ECO:0000313|RefSeq:XP_018108651.1};
GN Name=ell3.L {ECO:0000313|RefSeq:XP_018108651.1,
GN ECO:0000313|Xenbase:XB-GENE-999065};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018108651.1};
RN [1] {ECO:0000313|RefSeq:XP_018108651.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018108651.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018108651.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ELL/occludin family.
CC {ECO:0000256|ARBA:ARBA00009171, ECO:0000256|PROSITE-ProRule:PRU01324}.
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DR RefSeq; XP_018108651.1; XM_018253162.2.
DR AlphaFoldDB; A0A1L8H0R1; -.
DR STRING; 8355.A0A1L8H0R1; -.
DR PaxDb; 8355-A0A1L8H0R1; -.
DR GeneID; 100499400; -.
DR KEGG; xla:100499400; -.
DR AGR; Xenbase:XB-GENE-999065; -.
DR CTD; 100499400; -.
DR Xenbase; XB-GENE-999065; ell3.L.
DR OMA; DDFYKHV; -.
DR OrthoDB; 2910197at2759; -.
DR Proteomes; UP000186698; Chromosome 3L.
DR Bgee; 100499400; Expressed in pancreas and 15 other cell types or tissues.
DR GO; GO:0008023; C:transcription elongation factor complex; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.140.340; -; 1.
DR Gene3D; 1.10.10.2670; E3 ubiquitin-protein ligase; 1.
DR InterPro; IPR042065; E3_ELL-like.
DR InterPro; IPR031176; ELL/occludin.
DR InterPro; IPR019464; ELL_N.
DR InterPro; IPR010844; Occludin_ELL.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23288; OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL; 1.
DR PANTHER; PTHR23288:SF18; RNA POLYMERASE II ELONGATION FACTOR ELL3; 1.
DR Pfam; PF10390; ELL; 1.
DR Pfam; PF07303; Occludin_ELL; 1.
DR SUPFAM; SSF144292; occludin/ELL-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51980; OCEL; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|RefSeq:XP_018108651.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|RefSeq:XP_018108651.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 489..599
FT /note="OCEL"
FT /evidence="ECO:0000259|PROSITE:PS51980"
SQ SEQUENCE 600 AA; 68515 MW; 5A7E00C5680EA0DF CRC64;
MSRPGDELLG SLPYKTEPRR SPRLSLFHLK LTDSALRCLR DFQRRQGSGA SSLQPVITFQ
GNQGYIKIPS PSPGCEDRIR IFAFYLSRES KDKPQSSFEC IRQGTTWSGE KQLSCIGSIQ
DKITVCATDE SYQLTRDRVS QVEKETWSRT AIEIKPEASH RNKYVKIPTK NNMEASKEES
QCSQRPPVFL TPAAKKCNRV SVENRPLQEW IVHLLALKPY KKQKIISRLE KAGENLREQK
DLLATLDLVG KVNPKDGSYS LKEEFYTQVK TDWVGYSSEE RQHIESTLSR KHLNISASRN
IPTAMPAPPQ RTQQGPPSSY SSARGQHSES KRPPAAESTD NGSCKKMKTS HFDSRQRDSN
SPPALNSNSR HKTSPVPENH SVYSLHTHKN QSNHQSVPKS QHREHHKEKI PCEAQNSGKA
KPRGGTSQCS QGHKQTEWKK EEKKQQDSSE GEEEDDDWEE GALQLERCLC SPEEKPPLAE
PASPSDEIPD YCKKYRPITC ADQKQVYEKD FTTDYTEYLE LHAKIGKVLD HFVRLGSKMK
KLQEGTVEHK MAGKKILAEY KKFKLTYPAY REEKAKCEYL HHKLSHIKEL ILEYEKNPPT
//
