ID   A0A1L8H4G1_XENLA        Unreviewed;       306 AA.
AC   A0A1L8H4G1;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=LOC108710514 {ECO:0000313|RefSeq:XP_018107138.1};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018107138.1};
RN   [1] {ECO:0000313|RefSeq:XP_018107138.1}
RP   IDENTIFICATION.
RC   STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018107138.1};
RC   TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018107138.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688}.
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DR   RefSeq; XP_018107138.1; XM_018251649.2.
DR   AlphaFoldDB; A0A1L8H4G1; -.
DR   PaxDb; 8355-A0A1L8H4G1; -.
DR   GeneID; 108710514; -.
DR   KEGG; xla:108710514; -.
DR   OMA; YASIMTW; -.
DR   OrthoDB; 5259681at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 108710514; Expressed in heart.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   PANTHER; PTHR26452; OLFACTORY RECEPTOR; 1.
DR   PANTHER; PTHR26452:SF695; OLFACTORY RECEPTOR; 1.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU363047};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW   Olfaction {ECO:0000256|RuleBase:RU363047};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000313|RefSeq:XP_018107138.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000688};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM        25..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        138..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        200..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        236..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        271..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   DOMAIN          39..288
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   306 AA;  34726 MW;  B8B3D1D51A051577 CRC64;
     MKNQTLVSEF VLLGIQDFIN FKIPLFSLFL LIYIMTVWEN ILIIVLVSIS RNLKSPMYFF
     LQQLSLTDLL EATDTVPTLL QTGIYDRVLM SFVGCITQFS LFCVSESFEC LLLAVMSYDR
     YVAICIPLRY SSIMSHRVCV TFILMSWVLG LITALLLANF TATLQFRDLN TINHFFCDLL
     PILELSCSDT FFVQLEVTML SIPVAVFPLI FIIISYLCIA HAILKIVSNT GRQKAFSTCG
     SHLAVVSLFY GTLIAIYVVP HKKNSQTLSK LLSLLYTVVT PLINPLIYSL RNNDIRQALD
     HLVTRK
//