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Database: UniProt
Entry: A0A1L8H527_XENLA
LinkDB: A0A1L8H527_XENLA
Original site: A0A1L8H527_XENLA 
ID   A0A1L8H527_XENLA        Unreviewed;       454 AA.
AC   A0A1L8H527;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   11-DEC-2019, entry version 15.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OCT91217.1};
GN   Name=gabpa {ECO:0000313|Xenbase:XB-GENE-17331756};
GN   ORFNames=XELAEV_18014266mg {ECO:0000313|EMBL:OCT91217.1};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|EMBL:OCT91217.1, ECO:0000313|Proteomes:UP000186698};
RN   [1] {ECO:0000313|Proteomes:UP000186698}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J {ECO:0000313|Proteomes:UP000186698};
RX   PubMed=27762356; DOI=10.1038/nature19840;
RA   Session A.M., Uno Y., Kwon T., Chapman J.A., Toyoda A., Takahashi S.,
RA   Fukui A., Hikosaka A., Suzuki A., Kondo M., van Heeringen S.J., Quigley I.,
RA   Heinz S., Ogino H., Ochi H., Hellsten U., Lyons J.B., Simakov O.,
RA   Putnam N., Stites J., Kuroki Y., Tanaka T., Michiue T., Watanabe M.,
RA   Bogdanovic O., Lister R., Georgiou G., Paranjpe S.S., van Kruijsbergen I.,
RA   Shu S., Carlson J., Kinoshita T., Ohta Y., Mawaribuchi S., Jenkins J.,
RA   Grimwood J., Schmutz J., Mitros T., Mozaffari S.V., Suzuki Y., Haramoto Y.,
RA   Yamamoto T.S., Takagi C., Heald R., Miller K., Haudenschild C., Kitzman J.,
RA   Nakayama T., Izutsu Y., Robert J., Fortriede J., Burns K., Lotay V.,
RA   Karimi K., Yasuoka Y., Dichmann D.S., Flajnik M.F., Houston D.W.,
RA   Shendure J., DuPasquier L., Vize P.D., Zorn A.M., Ito M., Marcotte E.M.,
RA   Wallingford J.B., Ito Y., Asashima M., Ueno N., Matsuda Y., Veenstra G.J.,
RA   Fujiyama A., Harland R.M., Taira M., Rokhsar D.S.;
RT   "Genome evolution in the allotetraploid frog Xenopus laevis.";
RL   Nature 538:336-343(2016).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; CM004469; OCT91217.1; -; Genomic_DNA.
DR   RefSeq; XP_018104350.1; XM_018248861.1.
DR   GeneID; 378601; -.
DR   KEGG; xla:378601; -.
DR   CTD; 378601; -.
DR   Xenbase; XB-GENE-17331756; gabpa.
DR   KO; K09441; -.
DR   OrthoDB; 526256at2759; -.
DR   Proteomes; UP000186698; Chromosome 2s.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR024668; GABP_asu_N.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR016312; TF_GA-bd_asu.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF11620; GABP-alpha; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PIRSF; PIRSF001703; GABP_alpha; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT   DOMAIN          168..251
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   DOMAIN          321..401
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
SQ   SEQUENCE   454 AA;  51247 MW;  1906A5AD968134C3 CRC64;
     MTKREAEELI EIEIDGTEKT ECTEESIIEH TYSTAEFISQ SIDINEPIGN LKKLLEPRLQ
     CSLDAHEICL QDIQLDPDRS LFDQGVKTDG SVQLSVQVIS QQGLEPKLNI LEIVKAVETV
     EVVIDPDAHQ DAMEAELVEE AQVITLDGSK HITTISDETS EQVTRWAAAL EGYRKEQERL
     GIPYDPLQWS VDQVLHWVLW VMKEFGLTDI NVNSLGITGR ELCNLNQEDF FQRVPRGEIL
     WSHLELLRKY VLASQEQGGE IATVTIDHPV QIIPASIQPS AQTTIKVINS QTKVAKIQRA
     PRISGEDRSS PGNRTGNNGQ IQLWQFLLEL LTDKDARDCI SWVGDEGEFK LNQPELVAQK
     WGQRKNKPTM NYEKLSRALR YYYDGDMICK VQGKRFVYKF VCDLKTLIGY SAAELSRLVA
     ECEQKKMAKI QLHGIGQPVT AVTLATASLQ TEKD
//
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