ID   A0A1L8H7M8_XENLA        Unreviewed;       532 AA.
AC   A0A1L8H7M8;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Heterogeneous nuclear ribonucleoprotein R isoform X2 {ECO:0000313|RefSeq:XP_018103443.1};
GN   Name=hnrnpr.S {ECO:0000313|RefSeq:XP_018103443.1,
GN   ECO:0000313|Xenbase:XB-GENE-6252740};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018103443.1};
RN   [1] {ECO:0000313|RefSeq:XP_018103443.1}
RP   IDENTIFICATION.
RC   STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018103443.1};
RC   TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018103443.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   RefSeq; XP_018103443.1; XM_018247954.2.
DR   AlphaFoldDB; A0A1L8H7M8; -.
DR   STRING; 8355.A0A1L8H7M8; -.
DR   PaxDb; 8355-A0A1L8H7M8; -.
DR   GeneID; 100158425; -.
DR   AGR; Xenbase:XB-GENE-6252740; -.
DR   CTD; 100158425; -.
DR   Xenbase; XB-GENE-6252740; hnrnpr.S.
DR   OrthoDB; 3184171at2759; -.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 100158425; Expressed in blastula and 19 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd12488; RRM2_hnRNPR; 1.
DR   CDD; cd12494; RRM3_hnRNPR; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR   InterPro; IPR034411; hnRNPR_RRM2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR   PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR   PANTHER; PTHR21245:SF5; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R; 1.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR   PROSITE; PS50102; RRM; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW   Ribonucleoprotein {ECO:0000313|RefSeq:XP_018103443.1};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT   DOMAIN          64..143
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          145..227
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          240..310
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
SQ   SEQUENCE   532 AA;  59854 MW;  6F877175B5856662 CRC64;
     MKNSRPREKQ GNKTPESAKA PDEAQIKALL ERTGYTLDVT TGQRKYGGPP PESVSSGAQP
     GIGTEVFVGK IPRDLFEDEL VPLFEKAGPI WDLRLMMDPL SGQNRGYAFI TFCNKEAAQE
     AVKLCDNYEI RTGKHIGVCI SVANNRLFVG SIPKNKTKEN ILEEFSKVTE GLLDVILYHQ
     PDDKKKNRGF CFLEYEDHKT AAQARRRLMS GKVKVWGNVV TVEWADPVEE PDPEIMAKVK
     VLFVRNLSST VTEEILEKAF SVFGKLERVK KLKDYAFVHF DERDAAVRAM DEMNGAELEG
     EEIEIVLAKP PDKKRKERQA ARQASRGSSY DDYYYYPPPR MPLPGRGRGR GGRGGYSFPQ
     DYYGYEDYYD DYYSYDYHDY RGGYDDPYYG YDDGYPVRGR GGRGGRGGPP PPRGRSVPPQ
     RGGRTSYVPR GSPMGPPRGS RGGRGGPAQQ QPRGRNPRGI RGSRGGNVGG KRKADGYTQP
     DSKRRQTNNQ QNWGTQPIAQ QPLQQGGDYT GNYGYSNDNQ EFYQDTYGQQ WK
//