ID A0A1L8H9C2_XENLA Unreviewed; 637 AA.
AC A0A1L8H9C2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=E74 like ETS transcription factor 1 S homeolog isoform X1 {ECO:0000313|RefSeq:XP_018103560.1, ECO:0000313|RefSeq:XP_018103561.1};
GN Name=elf1.S {ECO:0000313|RefSeq:XP_018103560.1,
GN ECO:0000313|RefSeq:XP_018103561.1, ECO:0000313|RefSeq:XP_018103562.1,
GN ECO:0000313|Xenbase:XB-GENE-17339211};
GN Synonyms=elf-1 {ECO:0000313|RefSeq:XP_018103560.1,
GN ECO:0000313|RefSeq:XP_018103561.1}, xelf1
GN {ECO:0000313|RefSeq:XP_018103560.1, ECO:0000313|RefSeq:XP_018103561.1,
GN ECO:0000313|RefSeq:XP_018103562.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|RefSeq:XP_018103562.1};
RN [1] {ECO:0000313|RefSeq:XP_018103560.1, ECO:0000313|RefSeq:XP_018103561.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018103560.1,
RC ECO:0000313|RefSeq:XP_018103561.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018103560.1,
RC ECO:0000313|RefSeq:XP_018103561.1};
RG RefSeq;
RL Submitted (APR-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_018103560.1; XM_018248071.2.
DR RefSeq; XP_018103561.1; XM_018248072.2.
DR RefSeq; XP_018103562.1; XM_018248073.2.
DR STRING; 8355.A0A1L8H9C2; -.
DR PaxDb; 8355-A0A1L8H9C2; -.
DR GeneID; 380374; -.
DR AGR; Xenbase:XB-GENE-17339211; -.
DR CTD; 380374; -.
DR Xenbase; XB-GENE-17339211; elf1.S.
DR OMA; EXEASCH; -.
DR OrthoDB; 4245771at2759; -.
DR Proteomes; UP000186698; Chromosome 2S.
DR Bgee; 380374; Expressed in zone of skin and 19 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR022084; TF_Elf_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF156; ETS-RELATED TRANSCRIPTION FACTOR ELF-1; 1.
DR Pfam; PF12310; Elf-1_N; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 210..292
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 167..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 69713 MW; FCDF298DE699EDE5 CRC64;
MATAVQPNEL VFEFASNVME DEHQLGDPSI FPAVIVEHIP NADLLHTYSG LTCVDEPNHM
ITENSLDVAE EQIIEDDDLT LTVETSCLSV EASCNSGDET METIEAAEAL LNMDSPDSPM
LDEKRLANIF GSADDDLLIS PITHVSVTVD GIPEVVEINP NFYEENLESN LQEQPKRKKG
RKPRNPRPES PTTPNICVKK KNKDGKGNTI YLWEFLLALL QDKATCPKYI KWTQREKGIF
KLVDSKAVSR LWGKHKNKPD MNYETMGRAL RYYYQRGILA KVEGQRLVYQ FKEMPKDLVY
IDEEDSSSSA EYSGNLSSDF SLQHSSVTTP TRNQARAPKG SSNNASRASS ATVLKNGSSK
YLKLKEEIDP VQQQVSLIPS DLLRTIQSSS VSQPHPTQLY RTVHLMQPGQ AISEQAITCT
IQNDSLPGAQ TVRTIQSPGQ VPVVVSAGNQ QLHAVTLQTV PLTTVITSTD PVTGAGSQKF
ILQAMPSVSP MTILKENMVL QPQRTGSPPP SIVLSPSQVQ QVLSGNVQSL CNGTLSLPSS
PTFSASTPVM SFSTSTSPLL TQATGTVITS VIKSPETKQT LLPVSTTQAL QEGTPETAEQ
TEQKYQPPCV LVVASPNGFP SPLEIKQEND QWAFDSQ
//
