ID A0A1L8HCX7_XENLA Unreviewed; 207 AA.
AC A0A1L8HCX7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=AP-1 complex subunit sigma-2 isoform X2 {ECO:0000313|RefSeq:XP_018101521.1};
GN Name=ap1s2.L {ECO:0000313|RefSeq:XP_018101521.1,
GN ECO:0000313|Xenbase:XB-GENE-17338338};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018101521.1};
RN [1] {ECO:0000313|RefSeq:XP_018101521.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018101521.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018101521.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004180}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}.
CC -!- SIMILARITY: Belongs to the adaptor complexes small subunit family.
CC {ECO:0000256|ARBA:ARBA00006972}.
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DR RefSeq; XP_018101521.1; XM_018246032.2.
DR AlphaFoldDB; A0A1L8HCX7; -.
DR STRING; 8355.A0A1L8HCX7; -.
DR PaxDb; 8355-A0A1L8HCX7; -.
DR GeneID; 108707923; -.
DR AGR; Xenbase:XB-GENE-17338338; -.
DR CTD; 108707923; -.
DR Xenbase; XB-GENE-17338338; ap1s2.L.
DR OrthoDB; 998051at2759; -.
DR Proteomes; UP000186698; Chromosome 2L.
DR Bgee; 108707923; Expressed in muscle tissue and 20 other cell types or tissues.
DR GO; GO:0030121; C:AP-1 adaptor complex; IEA:InterPro.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR GO; GO:0035615; F:clathrin adaptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd14831; AP1_sigma; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR InterPro; IPR044733; AP1_sigma.
DR InterPro; IPR016635; AP_complex_ssu.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR000804; Clathrin_sm-chain_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR PANTHER; PTHR11753; ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY; 1.
DR PANTHER; PTHR11753:SF19; AP-1 COMPLEX SUBUNIT SIGMA-2; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00989; CLAT_ADAPTOR_S; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 50..190
FT /note="AP complex mu/sigma subunit"
FT /evidence="ECO:0000259|Pfam:PF01217"
SQ SEQUENCE 207 AA; 24541 MW; 12F923FE6A44C105 CRC64;
MLISLCLGTT SLLWCKKKKK RHRTSQIPFR EPREHRSSAW CFAEMPLGRQ MQFMLLFSRQ
GKLRLQKWYV PLSDKEKKKI TRELVQTVLA RKPKMCSFLE WRDLKIVYKR YASLYFCCAI
EDQDNELITL EIIHRYVELL DKYFGSVCEL DIIFNFEKAY FILDEFLLGG EVQETSKKNV
LKAIEQADLL QEEAETPRSV LEEIGLT
//
