ID A0A1L8HGG6_XENLA Unreviewed; 422 AA.
AC A0A1L8HGG6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000256|ARBA:ARBA00040055};
GN Name=wsb1.L {ECO:0000313|RefSeq:XP_018100304.1,
GN ECO:0000313|Xenbase:XB-GENE-5920544};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018100304.1};
RN [1] {ECO:0000313|RefSeq:XP_018100304.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018100304.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018100304.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_018100304.1; XM_018244815.2.
DR AlphaFoldDB; A0A1L8HGG6; -.
DR STRING; 8355.A0A1L8HGG6; -.
DR PaxDb; 8355-A0A1L8HGG6; -.
DR GeneID; 380049; -.
DR KEGG; xla:380049; -.
DR AGR; Xenbase:XB-GENE-5920544; -.
DR CTD; 380049; -.
DR Xenbase; XB-GENE-5920544; wsb1.L.
DR OMA; YVWDPHT; -.
DR OrthoDB; 5197664at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000186698; Chromosome 2L.
DR Bgee; 380049; Expressed in kidney and 19 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03733; SOCS_WSB_SWIP; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15622:SF12; WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15622; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50225; SOCS; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 386..422
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 422 AA; 47369 MW; 00FA7A3D42FFFBDB CRC64;
MASFPDFVNE NEIARSRTIG ELITPTSPFE QKYGRENWTV AFAPDGSYFA WSQGHRIVKL
VPWSRCLKNF TACSTKDGVN LTNGKLSRQN SDLGQKNKPI EHTIDCGDIV WSLAFGSSVP
EKQSRCVNIE WHRFKFGQDQ LLLATGLSNG RIKIWDVYTG KLLLNLMDHT EVVRDLTFAP
DGSLILVSAS RDKTLRVWDL KDDGNMMKVL RGHQNWVYCC AFSPDSSMVC SVGAGKAVFL
WDMDKYTMIR KLDGHYNDVV ACEFSPDGAL LATASHDTRV YVWDPHIGSI LFEFGHLFPP
PTPIFAGGDN GRWVKSVSFS HDGVHVASLA DDNLVRFWRI DRSYPVAVAP LSKGLCCAFS
TDGSVLAAGT QDGNAYFWST PKYVSSLQHL CRMAIRRVMT TNEVKKLPIP QKIKEYLTYQ
IM
//
