ID A0A1L8HGW3_XENLA Unreviewed; 533 AA.
AC A0A1L8HGW3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Interleukin-1 receptor type 1 isoform X1 {ECO:0000313|RefSeq:XP_018102562.1};
GN Name=LOC108708405 {ECO:0000313|RefSeq:XP_018102562.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|Proteomes:UP000186698, ECO:0000313|RefSeq:XP_018102562.1};
RN [1] {ECO:0000313|RefSeq:XP_018102562.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018102562.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018102562.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC {ECO:0000256|ARBA:ARBA00009752}.
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DR RefSeq; XP_018102562.1; XM_018247073.2.
DR AlphaFoldDB; A0A1L8HGW3; -.
DR STRING; 8355.A0A1L8HGW3; -.
DR PaxDb; 8355-A0A1L8HGW3; -.
DR GeneID; 108708405; -.
DR KEGG; xla:108708405; -.
DR OMA; CYDFLPK; -.
DR OrthoDB; 4322253at2759; -.
DR Proteomes; UP000186698; Chromosome 2L.
DR Bgee; 108708405; Expressed in spleen and 7 other cell types or tissues.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0004908; F:interleukin-1 receptor activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR004074; IL-1_rcpt_I/II-typ.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11890:SF26; INTERLEUKIN-1 RECEPTOR TYPE 1; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01536; INTRLKN1R12F.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS50104; TIR; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Receptor {ECO:0000313|RefSeq:XP_018102562.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
SQ SEQUENCE 533 AA; 61645 MW; CD6BF041E43C72CE CRC64;
MHPFAFLVIL SGLATYKAQL CRNEDVTCAE VQYVLNGEPI RLPCCGNRND SSNITWFKNG
SHIPFSSDPQ SRIHQNRNAL WFFPASLEDA GWYMCVLRDV TYCTRLIVFE NEKGLCYNRS
TLFPNWQYSE ATKIICPYVW DYVDISKAQI KWFKECQPLQ NDKYYALADA LTIQNAVKQD
EGLYTCVVQF EYSGTEYSLT RTIDLEITVA AASLLPFMRN PSNTINKVEL GSAISLRCEV
INGDEVLIMW TYNDSAVDEV YDTVITGDII PSMTEDGEPM VYSYLNFTEI KEEHYNKKFY
CEIFNAMTKA YVMLQRPDPN LQPFLIAFFV SLIFVIINIV IAVKIFKIDI VLWYRSSCFA
RKNKKDGKLY DAYVMYPKSL SETSSYPMDV FVLKVLPEVL EEQFSYRLFI FGRDVSPGEA
VSDVVDEAIS QSRRLVIVLG STQSKNYLKD DFEQQIAMYD ALIRNKIKVI LVELEKGMEY
SNMPESIQYI KQKQGAIRWK GDFMQSNTKF WKHMRYYMPP TSTKTCCTQT PIL
//
