ID A0A1L8P7B0_9LACT Unreviewed; 328 AA.
AC A0A1L8P7B0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE SubName: Full=2-oxoisovalerate dehydrogenase {ECO:0000313|EMBL:OJF91135.1};
GN ORFNames=AX762_11300 {ECO:0000313|EMBL:OJF91135.1};
OS Alkalibacterium sp. 20.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Alkalibacterium.
OX NCBI_TaxID=1798803 {ECO:0000313|EMBL:OJF91135.1, ECO:0000313|Proteomes:UP000182750};
RN [1] {ECO:0000313|EMBL:OJF91135.1, ECO:0000313|Proteomes:UP000182750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20 {ECO:0000313|EMBL:OJF91135.1,
RC ECO:0000313|Proteomes:UP000182750};
RA Wang D., Kot W., Qin Y., Naqvi K., Hansen L., Rensing C.;
RT "Genome sequencing of a beta-galactosidase producing bacteria
RT Alkalibacterium sp. 20.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJF91135.1}.
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DR EMBL; LSRN01000061; OJF91135.1; -; Genomic_DNA.
DR RefSeq; WP_071849009.1; NZ_LSRN01000061.1.
DR AlphaFoldDB; A0A1L8P7B0; -.
DR STRING; 1798803.AX762_11300; -.
DR OrthoDB; 9771835at2; -.
DR Proteomes; UP000182750; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000182750}.
FT DOMAIN 4..180
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 328 AA; 36015 MW; 6CE7C593B4B9740A CRC64;
MAMMTYLEAI HKGIEEEMAR DEKVVIFGED VGGMKGGVFG VTKGLAEKFG DERCFNTPLT
EGLIGGLAVG LGTVGYRAIG EFQFADYILP AVNQLISEAS RMRYRTKGDW TAPITFRAPY
GGGVRGGLYH SQSTEKVLFG QPGLRIVTPS SPRDAKALIK AAIRCDDPVL FYEHKRLYRL
LKEDVPEDDH VVPIDKANVV REGDDITVIG YGMVLNHALK AAEILSKEGY EAEVVDVRSI
YPLDKETLVK AAKKTGKVLL VTEDNLEGSV MSEISAIIAE EALFDLDAPI KRLAGPDSPS
MPYALPLERE FLVTEDKVLN AMRELAEF
//
