ID A0A1L8QP41_9ENTE Unreviewed; 388 AA.
AC A0A1L8QP41;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Class I SAM-dependent rRNA methyltransferase {ECO:0000313|EMBL:MCC9273217.1};
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:OJG09273.1};
GN ORFNames=K8V42_02880 {ECO:0000313|EMBL:MCC9273217.1}, RU93_GL000880
GN {ECO:0000313|EMBL:OJG09273.1};
OS Enterococcus aquimarinus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=328396 {ECO:0000313|EMBL:OJG09273.1, ECO:0000313|Proteomes:UP000182149};
RN [1] {ECO:0000313|EMBL:OJG09273.1, ECO:0000313|Proteomes:UP000182149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17690 {ECO:0000313|EMBL:OJG09273.1,
RC ECO:0000313|Proteomes:UP000182149};
RA Zhong Z., Sun Z., Liu W., Zhang W., Zhang H.;
RT "Draft genome sequences of 29 type strains of Enterococci.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MCC9273217.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=150 {ECO:0000313|EMBL:MCC9273217.1};
RX PubMed=33868800;
RA Gilroy R., Ravi A., Getino M., Pursley I., Horton D.L., Alikhan N.F.,
RA Baker D., Gharbi K., Hall N., Watson M., Adriaenssens E.M.,
RA Foster-Nyarko E., Jarju S., Secka A., Antonio M., Oren A., Chaudhuri R.R.,
RA La Ragione R., Hildebrand F., Pallen M.J.;
RT "Extensive microbial diversity within the chicken gut microbiome revealed
RT by metagenomics and culture.";
RL PeerJ 9:0-0(2021).
RN [3] {ECO:0000313|EMBL:MCC9273217.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=150 {ECO:0000313|EMBL:MCC9273217.1};
RA Gilroy R.;
RL Submitted (NOV-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJG09273.1}.
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DR EMBL; JAJJVO010000049; MCC9273217.1; -; Genomic_DNA.
DR EMBL; JXKD01000018; OJG09273.1; -; Genomic_DNA.
DR RefSeq; WP_071875579.1; NZ_JXKD01000018.1.
DR AlphaFoldDB; A0A1L8QP41; -.
DR STRING; 328396.RU93_GL000880; -.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000182149; Unassembled WGS sequence.
DR Proteomes; UP000813384; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43042:SF3; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K; 1.
DR PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:OJG09273.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000182149};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OJG09273.1}.
FT DOMAIN 3..63
FT /note="RlmI-like PUA"
FT /evidence="ECO:0000259|Pfam:PF17785"
FT DOMAIN 161..346
FT /note="S-adenosylmethionine-dependent methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF10672"
SQ SEQUENCE 388 AA; 43846 MW; A219B79CEAF25211 CRC64;
MKIQLTLNGS KKIKQGYPLI QLEDLVNPKW SNDWVELMNP QGEYVGTGYL GKQNKGIGWV
LTREKTPIDD SFFQALFEQA KKKRQPYYLD PLTSAFRLFN GEGDGLGGLI IDLYLEHAVF
SWYNETLYQK KPSIVAAFQQ AFPEIKGAYE KIRFEGDYPE SLHLYGETAA EPTLIQENGV
TYATYLNEGL MTGIFLDQKE VRGSLVDGLA SGKTVLNMFS YTGAFSVAAV MGGAAKTTSV
DLAKRSVPKT REQFEVNGID PDTQQIHVMD TFEYFKYAKR KELTFEVIIL DPPSFARNKK
KTFSVAKNYG ELIEDSVDLL TDEGIIIAST NAANVSPRQF QQMIEKAFAK KEVHYQKIKH
YSLPSDFATV ATFPEGDYLK VYCYEVKK
//
