ID A0A1L9N500_ASPTC Unreviewed; 732 AA.
AC A0A1L9N500;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Dipeptidyl-peptidase V {ECO:0000256|ARBA:ARBA00032829};
GN ORFNames=ASPTUDRAFT_201502 {ECO:0000313|EMBL:OJI84182.1};
OS Aspergillus tubingensis (strain CBS 134.48).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=767770 {ECO:0000313|EMBL:OJI84182.1, ECO:0000313|Proteomes:UP000184304};
RN [1] {ECO:0000313|Proteomes:UP000184304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 134.48 {ECO:0000313|Proteomes:UP000184304};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SIMILARITY: Belongs to the peptidase S9C family.
CC {ECO:0000256|ARBA:ARBA00010040}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV878203; OJI84182.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9N500; -.
DR STRING; 767770.A0A1L9N500; -.
DR VEuPathDB; FungiDB:ASPTUDRAFT_201502; -.
DR OMA; YKHWDEW; -.
DR Proteomes; UP000184304; Unassembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR PANTHER; PTHR42776:SF28; DIPEPTIDYL-PEPTIDASE 5; 1.
DR PANTHER; PTHR42776; SERINE PEPTIDASE S9 FAMILY MEMBER; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000184304}.
FT DOMAIN 490..699
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 732 AA; 80488 MW; 76B3FB75C4F2AA8D CRC64;
MTIRSMKFTP EVLLGAPRRS GPVPNASGTL AVYTQTTYSF ESHSKTNEIR VLDIATGRSA
LITNDAGASC PQWLGDSNQL VWLKAKANGN TSFIVGDARE ADKTYTAGTV PGPVSDLKVT
VVEPGKIGFA VTGKANPDGT LHNPHDAKKP ISTGKLFTSL YVRHWDSYIE PQKNAIWYGL
LQRAPLSPAT RQAGKYSVSG LTNLISVSGL AGVEAPIPPF GGTGDFDISP SAIVFVAKDP
DLNPATHTSC SCYYCPMFSW TGVNALEAKV CAVKGLEGAM SSPILTSDGS SIVLLAMRED
GYESDKRRIL YVPNPWNGEM IEVFASADGE GLWDSSPSGL TFSNDDQSLF IQVEEYGRGV
LYQLPMADIR HATPDKLKKI TNAGYVTDVY PASKQSTKLL ISSTSLVDNS VWSIVDPESP
SDVRVISSIG RNGAVFGLSP SQVDEIWYRG ANDTPVHAWV VKPSNFKPGK KYPLAYLIHG
GPQGAWCDQW STRWNPAVFA EQGYVVVTPN PRGSTSYGQK FTDEIRGNYG SLPYIDLEKG
FDYIENNLEY VDTSRAVALG ASFGGYMVNW IQGHPLGRRF KALVTHDGIF SMTSMLSTEE
LYFPVRDLKG PLWKVPENWE RWDPSRHTAN WQTPHLVIHN ELDYRLTIAE GLAAFNVLQM
RGVESAFLTF PDENHWVLNP ENSLMWHHTV LNWINKYVGL PPASREFAEF STTKQTSMER
RLQQVTLDGA SS
//
