ID A0A1L9NNU3_ASPTC Unreviewed; 1409 AA.
AC A0A1L9NNU3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=IPT/TIG domain-containing protein {ECO:0000259|Pfam:PF01833};
GN ORFNames=ASPTUDRAFT_279626 {ECO:0000313|EMBL:OJI90976.1};
OS Aspergillus tubingensis (strain CBS 134.48).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=767770 {ECO:0000313|EMBL:OJI90976.1, ECO:0000313|Proteomes:UP000184304};
RN [1] {ECO:0000313|Proteomes:UP000184304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 134.48 {ECO:0000313|Proteomes:UP000184304};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
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DR EMBL; KV878176; OJI90976.1; -; Genomic_DNA.
DR STRING; 767770.A0A1L9NNU3; -.
DR VEuPathDB; FungiDB:ASPTUDRAFT_279626; -.
DR OMA; HPMMRRI; -.
DR Proteomes; UP000184304; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00102; IPT; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR24171; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED; 1.
DR PANTHER; PTHR24171:SF9; L-ASPARAGINASE; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00248; ANK; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1361..1382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 819..887
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|Pfam:PF01833"
FT REPEAT 1010..1042
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1043..1075
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 48..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1119..1184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..580
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1119..1135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1409 AA; 153604 MW; A15550E118026A07 CRC64;
MMGSAEAASS PAFPFLDPIV VDDEMGHPYQ DEDMDFLDTA RLQMSAENAG RDFDDIFSRA
TSSRPVAESE PSCLSPSELS LKRSYQDQDA LRQVNVVSSD SPAESPDGSS PSSSSTSPRN
HLRNPSVTSS ASVVHSENTV MPFGYATEDW MNPDLSSVKE ESLFGLDLSL PNLDGAFPTD
TDLESSNKAM DAAFDFESAA SSPSPLKSES AQPRIAKRSK SQMRSVSSTS ARHSASSMNG
STFFPRNTKE PSPFSVSRSF SQAKSPLGPW GGHSPSSLLE ESFGGINMNG GSPLTPGLNF
GPSSFPFGVN FAPSPSPTTV KQETTQRHML TVHPTSLKSR VETQIPIRLT LFPLPNGVKK
VRLPSHTISK PKFLAPPTVE RSPEIVELHT SLVCTSAMQD QEKLKKAFAR ARGDNSYRSS
SSSPRSAEDM QEDDKPLDGG EVKICPGCIQ RERKRAFRKK QRKPEEDELF QKDEEKRVIV
FNTNEVKEWA EPSKNAMPSF GDAPMPNIPP GAMQVELPMR IACYCRHQNE KLGFQVIFTV
KDYKDNVVAQ AITNSIMITD DHKTHAPPAP PAPGPSPSLP DGTQLPGVGV FPSSPSVDTG
KSSAPSQQAS QSSSATDLQG LQQRFNTQYL TSGSFPVSQS STNGTTTNTQ TPRSLSRQTS
PNDFQGPMSK RRKHSNSGRL PSELTMTKLE NTQSSGSVSS SSAPNNDPPF PSTRGFASPA
ERPFVTASAI SNQFPNGPPT PNGADTNPFL NTMQQQSLDN FIQQQLMSAP NSAQPSRPGT
PGGSRNNFQD PNYNISLGPN TSSPMWPPLT NAGNRLPSVI HKLVPAEGSI TGGTEVTLLG
SGFYPGMEVV FGDTLATTTT FWGDKCLNCL TPPALQPGLV AVVFKHEHPT FGQMQPTQPL
MPKQQQFFRY VDDRELQMYR LALGILGQKL GSQADAFQTA QQIMGSDMKG VFNLQKDFPG
GSGGGHQRQA AGLESQVSLG DLDGRMWKYL EFVDLDDSPR PPRYNSRSAT GQTLLHFAAS
LGLTRFVAGL LARGANPDLQ DNTGNTPMHF AALNGHAHIV NRLRLAGANP NARSIRGFTP
ADLATTLPAH QAALIPARHY RSRSVGSLSS SRRRHSSSAS LHSLWDSSSV SGSFDHAVED
SDDSEDDDDV IDYSASRRSS MHHERPVSIP GPEQPAESDD ARPFSPPAAL VAWRNQLQAQ
INQFQQSVAN AFPNLPALPP MPALPDYQAH PMMRRITNLV PHRPSTARSA KDGWWDMLTG
NSAPTGTELP SYEELYPHKE NEDDEQTTRL KKSSMLQAAT EAALDQHFEA QASTSEVVRT
KPESEDIKDI RIGRKVISRE QQKHLREQQA RRMKGLGSDR NLYFIWIPLL LLVICAWIRS
YVPGIWEGFT SGYEFVKAQY AQRALEVGH
//
