ID A0A1L9NP78_ASPTC Unreviewed; 859 AA.
AC A0A1L9NP78;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=MHD domain-containing protein {ECO:0000259|PROSITE:PS51072};
GN ORFNames=ASPTUDRAFT_291171 {ECO:0000313|EMBL:OJI91095.1};
OS Aspergillus tubingensis (strain CBS 134.48).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=767770 {ECO:0000313|EMBL:OJI91095.1, ECO:0000313|Proteomes:UP000184304};
RN [1] {ECO:0000313|Proteomes:UP000184304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 134.48 {ECO:0000313|Proteomes:UP000184304};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
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DR EMBL; KV878176; OJI91095.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9NP78; -.
DR STRING; 767770.A0A1L9NP78; -.
DR VEuPathDB; FungiDB:ASPTUDRAFT_291171; -.
DR OMA; FQTHEVD; -.
DR Proteomes; UP000184304; Unassembled WGS sequence.
DR CDD; cd09264; AP_Syp1_MHD; 1.
DR CDD; cd07650; F-BAR_Syp1p_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR028565; MHD.
DR InterPro; IPR018808; Muniscin_C.
DR InterPro; IPR049609; Syp1-like_MHD.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR23065:SF54; SUPPRESSOR OF YEAST PROFILIN DELETION; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF10291; muHD; 1.
DR SMART; SM00055; FCH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51072; MHD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000184304}.
FT DOMAIN 569..839
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
FT REGION 240..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..841
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..261
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 859 AA; 93640 MW; 34EA9DEBC72E20B0 CRC64;
MELSRQEYPA LLASLQPGQA TSVLNDRIRI INKVNADIAD WLQERRRIEE LYAQGLRKLA
HRPQLDNGAA LGVFQIPWQR IITATESIAS SHETFAHKIE EDVERPLREY STKNRELSSM
TGIQSDLAGL AKNYEASQKK VEKAREKGPK GADKLASAVA AAEEISQQWD SRAPFVFEQL
QAADEGRLNH LRDALTQLET HETDQVERCR QAAESCLNVL LNVETADEIK TFAAKINGGR
PVVPRRQQTT SPPPVAPLSP PPRLQDDAAS QRSEHSGPVR TPPAPEPRHN TPLGGLKRLG
TVMNRRRSIV QPSSAGPFFS DKKHRSPFAS FKRGDSRELQ IPETPTEGME RPSTAMTTQD
TEPPAISNES HDHEGFAGAT STAMPQSAPA TANGATSHEA PSEEITAAAG VSRNEPRVDS
EGFTERPETI DEITRAQREA AGLEEPGMNL TIRDQPIFED EDQAKQAMDD MANQLRMQSG
VRRNAGTLRG RRDVRNTVFI PTPAPGNDLP AIPSTLDTSA PTSPSLQARH VASPSTATDD
HAMSDTTSIR SSHTLHSAPG PVLHPDLHEP GLNASIIDTV SAWFTEGAVS KSFVVGELAL
AYNATPDVTP GSTRVRLDNF QILEKVAANP HFVTEDKGKD QFDEKRGEYE VNLASIARSS
PTVAFKYQIH MEPSVAAAYC PVIFKPVWNL EEHQASAIIY YSLNSSFTSA PGGSITLRNL
VLTVNLDTSP VEGREVAHAT AAVMYPNTGA TFRRKQSAVT WKIPEFEVKA GSDAKLLVRF
STTASWPRQG KVDAKFEVHT LDDGSRLGIS TASPTNLAKG SDPFADEEAG SQTPELQPSV
EWKNVPTARK LLGGKYVSS
//
