ID A0A1L9PCV0_ASPVE Unreviewed; 1105 AA.
AC A0A1L9PCV0;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Poly A polymerase head domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPVEDRAFT_125164 {ECO:0000313|EMBL:OJI99338.1};
OS Aspergillus versicolor CBS 583.65.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=1036611 {ECO:0000313|EMBL:OJI99338.1, ECO:0000313|Proteomes:UP000184073};
RN [1] {ECO:0000313|Proteomes:UP000184073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 583.65 {ECO:0000313|Proteomes:UP000184073};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SIMILARITY: Belongs to the TTI2 family.
CC {ECO:0000256|ARBA:ARBA00034736}.
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|ARBA:ARBA00007265,
CC ECO:0000256|RuleBase:RU003953}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV878126; OJI99338.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9PCV0; -.
DR STRING; 1036611.A0A1L9PCV0; -.
DR VEuPathDB; FungiDB:ASPVEDRAFT_125164; -.
DR OrthoDB; 5402987at2759; -.
DR Proteomes; UP000184073; Unassembled WGS sequence.
DR GO; GO:0110078; C:TTT Hsp90 cochaperone complex; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001680; P:tRNA 3'-terminal CCA addition; IEA:UniProt.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR InterPro; IPR018870; Tti2.
DR PANTHER; PTHR13734:SF5; CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13734; TRNA-NUCLEOTIDYLTRANSFERASE; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR Pfam; PF10521; Tti2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000184073};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 54..207
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 234..294
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
FT REGION 1007..1029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1105 AA; 124359 MW; E6B02F2EB0244473 CRC64;
MISAADETAQ QPPTIELTPL ENTFKTLLLD VCQYIQERDV AAGKTSADTS KTVLRFTGGW
VRDKLLGVES HDIDVAINNM TGYQFGNILI EYLETPGNLD KYRKGNEKDE LEKAFSSLHK
IEANPEKSKH LETVTTKIFG YDVDLVNLRK ETYTENSRTP QMEFGSAEED ALRRDATINA
LFYNLNESKV EDLTKRGLDD MRDQIIRTPL EPYQTFKDDP LRVLRLIRFA SRLGFRIDKD
TESAMQHSDI GTALKLKISR ERVGIEVEKM LRGPDPRGAL NTIDRLNLYP IIFTNYQDDA
TADPSSWSLA YNALHRFLFS TEELEAVGRL RTLLIRDSLQ EYYAWVIAAF APWSAVPGRP
PKGKPLPPRM AEAARDALRS DNKTVTILKH AASNWRNIIN VKTEVVDGKL QGTAAEIRQQ
VGLHIRSWGM DWRLCVLLSL LQEIMQGGDF AAVVQSYDKF LTYILEQDLQ DVCELKPIVN
GGEVMGAIPA KKGPWVSKAL ELAIQWQLLH PDIQDKQKAL EYLESKKGEF ELRNAARGAL
RQQKPALIPE SILSNVTIPA AVDQLWQEIS THDNSDHAKI LEDLLVAQGF LSGKALESVS
DADKAAINRL YEWATQMESQ QRSTLAIPVI SSLAKLLPIE DAESLDDVLI ALASFTSEQD
AWTTPETYTT STALLNDFVE RSEASHFWGT VESLLKTRIR PLFAKTKNPA ITESGRKNFH
PIPLPRFDMS ILDPETKPWK MYDVYITTVF SWVVNQYKHT DREHLESHFP LLVPPILTMI
DDDSLSFKRH GCILLSHFLI PIQESKSDIL RRTNLSSVFE DAIRPCFHSL PTITPEDDSI
QLLAAAYPAL RSLLQTSYRS ALTQDSQPTP IKHMKDNETF ISATTKTLRD HLIPSFHHIS
SADITSTSTF ASFPHPRLST LLLNQVAITC ADLGIHTTKY LQDIVPLVYS TLSNMFGTTH
PPLLLSALSV ARAAILNAYP RIWRWRGEII GAICSCWVNV LDDEEESKTA GTRAPKDKTS
ASPPRDENKT AELMRLKKEL QGSVYLLRYA LENPAHIDSD EGQREAKENI GREIQMLVDA
DDSLKECLLA DVDPDDGNYF GFGSI
//
