ID A0A1L9PR50_ASPVE Unreviewed; 1107 AA.
AC A0A1L9PR50;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=ASPVEDRAFT_135907 {ECO:0000313|EMBL:OJJ03912.1};
OS Aspergillus versicolor CBS 583.65.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=1036611 {ECO:0000313|EMBL:OJJ03912.1, ECO:0000313|Proteomes:UP000184073};
RN [1] {ECO:0000313|Proteomes:UP000184073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 583.65 {ECO:0000313|Proteomes:UP000184073};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
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DR EMBL; KV878131; OJJ03912.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9PR50; -.
DR STRING; 1036611.A0A1L9PR50; -.
DR VEuPathDB; FungiDB:ASPVEDRAFT_135907; -.
DR OrthoDB; 1818010at2759; -.
DR Proteomes; UP000184073; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05918; A_NRPS_SidN3_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF3; SIDEROPHORE SYNTHETASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000184073}.
FT DOMAIN 589..666
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1107 AA; 121612 MW; 04A58926169042F4 CRC64;
METTSPTAVD CQLQKAGAFV LNAEVDTGDE PYLDLASYIP KKALQNTRRD PVHSCVNEIY
EAQFQARPDA PAVCACDGSL TYRELNNCSA VLANKLRRQG VKAEGLVALL FEKSKLMAVA
MHAVIKAGGA FMMWDPSFPV ARLRGMFGES GAHLVLASAG NSQMASEISD NVIVVDEIHP
LDTAPLDPGN RPENALYSVY TSGSTGKPKG FLIEHKAVCT CALALGSEMG ITENSRFLQF
SSNSFDLAAF EHLLPFLFGA CLCIPSESER KSDLNRALDS YGITHAILTP SVSRLIDPKQ
LTALRTLLLG GEASTQEDVR RWTPYVQLLN GYSPAEAGCL NVVNPGATQA SPNNIGFPLT
ITPWVVDPEN HNRLMRAGDV GELVIQGHTL ARGYFGPPER SAAAFIDTPT WARKLACESY
GRMYKTGDLV RFDVEDGSLH YVGRKDLQVK VRGQRLELAE VEFALQQCFP SPHSVLAEVI
VTDGREPSLL GFVCRQGQRQ LMPIAPQSDE RGLFLVPDSK FCAEAQVALT AMGNTLPSYM
VPSDLLLISH LPMLPSGKTD RGSLRTLAAG LNPAERRGYS SVLRQHRDEP RDELEHLLLV
LWATSLSLAA TQVGVKDNFF HLGGSSLDAI HLAAGIRKMG FSELSSAIVF NNPTIREMAD
TLKVIKASSQ PQNTSPLASF ELDSLLAAEL LRKVGISPDD LECGFLPVTP FQRKSCLLKP
MHLTIDISGI DHARLEAAWT IVQQNHISLR SIYVMQNGDI YQAFLRRPGS ASIPIFRCEE
RVGDYAARFC DHDTRNILDG RPWWSLSRVD SHTESSLVLR TTHAQIDAMT LDAIFKDFMA
VFEGQELSQR GLEFPRYMQS RLTHNTSTAA TAFWSKFLDG SEITRPILLD PSLVVDPESE
SMVFVSREMT AMTPPAGITL AAVFRAAWAF VLSQYTKEDD VVFGEFVEGR SLPISDVDKV
TGCTAAEAPM RITIPSGASV LDLLHHSQKQ HVSRIPYETC ELEDIIPRCT SWPIDTAFSH
ILILENVDVV PPVVLDGQLR KHRWAFHGRL EDVHVQLFPG HEKLQVGISG PAIRLSESIA
TLLVDKLEAA FRDFITRPEA PLSDIAS
//
