ID A0A1L9PS08_ASPVE Unreviewed; 697 AA.
AC A0A1L9PS08;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=N-acetylglucosaminylphosphatidylinositol deacetylase {ECO:0000256|ARBA:ARBA00012176};
DE EC=3.5.1.89 {ECO:0000256|ARBA:ARBA00012176};
GN ORFNames=ASPVEDRAFT_85629 {ECO:0000313|EMBL:OJJ04225.1};
OS Aspergillus versicolor CBS 583.65.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=1036611 {ECO:0000313|EMBL:OJJ04225.1, ECO:0000313|Proteomes:UP000184073};
RN [1] {ECO:0000313|Proteomes:UP000184073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 583.65 {ECO:0000313|Proteomes:UP000184073};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SIMILARITY: Belongs to the PIGL family.
CC {ECO:0000256|ARBA:ARBA00006066}.
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DR EMBL; KV878131; OJJ04225.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9PS08; -.
DR STRING; 1036611.A0A1L9PS08; -.
DR VEuPathDB; FungiDB:ASPVEDRAFT_85629; -.
DR OrthoDB; 1874888at2759; -.
DR UniPathway; UPA00280; -.
DR Proteomes; UP000184073; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR CDD; cd12087; TM_EGFR-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.10320; LmbE-like; 1.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR003737; GlcNAc_PI_deacetylase-related.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR024078; LmbE-like_dom_sf.
DR PANTHER; PTHR12993; N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED; 1.
DR PANTHER; PTHR12993:SF23; N-ACETYLGLUCOSAMINYLPHOSPHATIDYLINOSITOL DEACETYLASE; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF02585; PIG-L; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF102588; LmbE-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184073};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..697
FT /note="N-acetylglucosaminylphosphatidylinositol
FT deacetylase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009887317"
FT TRANSMEM 595..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 379..490
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|Pfam:PF00754"
FT REGION 366..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 697 AA; 74794 MW; 4E847044944C10C3 CRC64;
MKHYTLLSSL LIYASLSYGQ ILNIVAHQDD DLLFISPDLL HYIQTGQEVR TVFITAGDSG
RDESYWQGRE AGARSAYAVM SAAPDSWTEK DAGIPGHQAS LFSLDQDPGI SLVFLRLPDG
NLLGQGFEET GSESLQKLWE GGISRIRTVS GSGSYTKGEL VDALVHLTSE FGPERVNTLD
YVQEYGDGDH SDHHSTGYFV AEALKRYGNE STLAGYVGYP VVNKPKNVEG ADLLDKKFAY
YAYASHDPVV CDSDMACADP TFAPYYPEWL ERRHTVDTSP IANAGTVQVA GLDTVVTLDG
SASSDPSDRP LVYEWTQVSG PAVDLKDAET SHPYFTTPSD PDSLSFELVV KNKQTSSSPA
VVRVTTMQHP ENIAPKARVT ASSSNDGSSQ TPDKATDGST GGFPAGHSNE WATDGGKAGS
WLTLSWESPQ TISRIALYDR PNLQDHITRA VVEFDGGERI EVGELDNYGT LRTVNAAGRT
ARNLTVRITE VSPSTTNVGL AEIQVFGTSC HAIFLRTFTV FETSPAGLPS ASSVGCWQGW
SAWTVYRTRP DASTASTTTT DTTTTTTTTA EATPTPTDGS EEADSESEST SGQDWIAGAV
VGPVAGVAII GVAVFFYLRS KKRLLAAPVQ QVYYQGPHYG PAQAAQAAPK NAVSLGTSEL
ANAQYRYGST GAATETQGFP VAEMPSTRQT HELSSRR
//
