ID A0A1L9QRY8_9CYAN Unreviewed; 670 AA.
AC A0A1L9QRY8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Guanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BI308_12055 {ECO:0000313|EMBL:OJJ25347.1};
OS Roseofilum reptotaenium AO1-A.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Desertifilales; Desertifilaceae;
OC Roseofilum.
OX NCBI_TaxID=1925591 {ECO:0000313|EMBL:OJJ25347.1, ECO:0000313|Proteomes:UP000183940};
RN [1] {ECO:0000313|EMBL:OJJ25347.1, ECO:0000313|Proteomes:UP000183940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AO1-A {ECO:0000313|EMBL:OJJ25347.1};
RA Buerger P., Wood-Charlson E.M., Weynberg K.D., Willis B., Van Oppen M.J.;
RT "CRISPR-Cas defence system in Roseofilum reptotaenium: evidence of a
RT bacteriophage-cyanobacterium arms race in the coral black band disease.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-4/guanylyl cyclase
CC family. {ECO:0000256|RuleBase:RU000405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJJ25347.1}.
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DR EMBL; MLAW01000018; OJJ25347.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9QRY8; -.
DR STRING; 1925591.BI308_12055; -.
DR Proteomes; UP000183940; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR018297; A/G_cyclase_CS.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR11920:SF335; GUANYLATE CYCLASE 32E; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS00452; GUANYLATE_CYCLASE_1; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils}; Lyase {ECO:0000256|RuleBase:RU000405};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000183940};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 367..427
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 485..612
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT COILED 419..453
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 670 AA; 75092 MW; 91E1FC9AC1D62EFB CRC64;
MIPRLSLSNQ LSLRAVLIVP FIVQISAAVG ITGYLSWRNG QQAVNQLAGQ LRDEVTKRTQ
QHLTDYLQEP PQINQVNRQA VEAGKLDEDN VQQLQDHFWQ QIQLFPRLRE LYIGKPNGGY
FAISREADQS LIVKEVLGED DQIGRFYALS ENGDRQNLIR ETAPYDPRQR PWYQAALESR
TGTWSDIYLF RYGALGITAS ELFLNADGSM GGVMAVDLVL SGMSEFLSTI EVSPSGKIFI
IERSGLLVAS SSTVPPFLLG AGGKNPQRLM ARESSDRLIR ETAEFLMQER QLESIEEVKQ
LNFGQSSDRS FVQVSPYQDN LGLDWLIVVV VPESDFMGQI YANTWRTIQL CSLALLIATG
FGWMSAHWIS EPIMQLIDGS QKLAKAALSR CNNDTLAQNV EVRGVQEVKI LAHSFNQMAS
QLQESFAALE RSNQELELRV EKRTADLRRE REKSEELLLN ILPEAIAEKL KQETQAIAEY
FESVTILFSD IVGFTTLSAR LAPIDLVNCL NEMFSSFDHL AEKHGLEKIK TIGDAYMMVG
GLPIPQPDHA AAMAAMALDM QKVMQDFTLE NGEALQIRIG IHTGPVVAGV IGVRKFSYDL
WGDTVNTASR MESSGTAGRI HVSYQVYEVL KDRFQFEERG IISVKGKGEM KTYWLVQSYS
ALRFALGNRE
//
