ID A0A1L9RIT3_ASPWE Unreviewed; 936 AA.
AC A0A1L9RIT3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPWEDRAFT_479428 {ECO:0000313|EMBL:OJJ34835.1};
OS Aspergillus wentii DTO 134E9.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Cremei.
OX NCBI_TaxID=1073089 {ECO:0000313|EMBL:OJJ34835.1, ECO:0000313|Proteomes:UP000184383};
RN [1] {ECO:0000313|Proteomes:UP000184383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DTO 134E9 {ECO:0000313|Proteomes:UP000184383};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR EMBL; KV878212; OJJ34835.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9RIT3; -.
DR STRING; 1073089.A0A1L9RIT3; -.
DR VEuPathDB; FungiDB:ASPWEDRAFT_479428; -.
DR OrthoDB; 276400at2759; -.
DR Proteomes; UP000184383; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000184383};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 349..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..396
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 105149 MW; 34816D4429A1B3D0 CRC64;
MEWQPQDDQL RLLACCLRDS LNAYNRNAQK QAEQMLVQAT SSPDYVNYIT YLFCTPRTPQ
AVGMDEHTYN MVRFAAGMNL KTKIRVAYPT IAPASLAYIR SATLIGLRDS NFQVRSSAGS
IITEFVSQAG LLAWPEVLHE LLTLVGNASG DTPLVAQEAA MSALAKVCED NRKILDRDYQ
GQRPLDVIIP KLMEFTSSQS PKVRSMALGT IHVFLPHRPQ ALIASLDLFL SQLFQLSNDT
STDVRRTVCQ SFAQLVDFAP ENLIPHMEGL VNYIIVQQQN QEDPELALDA AEFWLVAGEQ
QKLQQPLAPH MSKIVPVLLQ SMVYDEDDAI RLTGDNDDAD VEDRAEDLKP QFAKSKSDKI
ETKPNAQANG NAPPEEDDED DLSDGEIEDS EFGDDPEDEW TLRKCSAAAL DVFSNVYHQP
IFEVILPYLK ETLRHDQWPH REAAVLTLGA VADGCMDAVT PHLYELVPYL ISLLNDAQPV
VRQITCWCLG RYSEWASHLV DPSERVRYFE PMMEGILRRM LDGNKKVQEA AASAFASLEE
KSDASLVPYC EPILRQFVQC FDKYKDRNMY ILYDCIQTLA ECVMGELAEP HLVDILMPAL
IDRYNKVSDQ SRELFPLLEC LGYIAAAYGD AFAPFAPPLF QRCIKIIYEN LQEYMASVNN
QAIDEPDKDF LVTSLDLLSA IIQAIDPQKS GELVGNSQPR FFDLLCFCME DPNYEVRQSS
YALLGDCAIN IFPQLEPFIP NIMPTLIKQL DLDLIRDDER HTGFSVLNNA CWSCGEIAVN
EKASLSPYAD KLYRGLSAII TNEEVIDSVN ENAAMALGRL GICCSDQLAP HLGEYATSFL
KSMNKIDFTR EKASAFLGFN QVVMKNPQAM ESTLADYFQS IAAFPSKSLS QDDYRDIQSS
FQQVLQGYKN MIPNFDSFLS QLPPPVTQKL RSVYQV
//
