ID A0A1L9RRU7_ASPWE Unreviewed; 1092 AA.
AC A0A1L9RRU7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Poly A polymerase head domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPWEDRAFT_50721 {ECO:0000313|EMBL:OJJ37593.1};
OS Aspergillus wentii DTO 134E9.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Cremei.
OX NCBI_TaxID=1073089 {ECO:0000313|EMBL:OJJ37593.1, ECO:0000313|Proteomes:UP000184383};
RN [1] {ECO:0000313|Proteomes:UP000184383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DTO 134E9 {ECO:0000313|Proteomes:UP000184383};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SIMILARITY: Belongs to the TTI2 family.
CC {ECO:0000256|ARBA:ARBA00034736}.
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|ARBA:ARBA00007265,
CC ECO:0000256|RuleBase:RU003953}.
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DR EMBL; KV878211; OJJ37593.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9RRU7; -.
DR STRING; 1073089.A0A1L9RRU7; -.
DR VEuPathDB; FungiDB:ASPWEDRAFT_50721; -.
DR OrthoDB; 5402987at2759; -.
DR Proteomes; UP000184383; Unassembled WGS sequence.
DR GO; GO:0110078; C:TTT Hsp90 cochaperone complex; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001680; P:tRNA 3'-terminal CCA addition; IEA:UniProt.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR InterPro; IPR018870; Tti2.
DR PANTHER; PTHR13734:SF5; CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13734; TRNA-NUCLEOTIDYLTRANSFERASE; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR Pfam; PF10521; Tti2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000184383};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 53..206
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 233..292
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
SQ SEQUENCE 1092 AA; 122716 MW; 777A1BA1C64E3F94 CRC64;
MAQASDQAMH SLPTIQLTPI ENTLKTLLLD VAHYIRGREL ALNSHVNVPQ TELRFTGGWV
RDKLLGIDSH DIDVGISNMT GYQYGMALKE YLDIPNNLEK YKKNHPDGEL KDAIVSLHKI
DANPEKSKHL ETVTTKIFGL EIDLVNLRKE TYSEDSRNPQ MEFGTAEEDA LRRDATINAL
FYNLNESKVE DLTRRGFEDM KNGIVRTPME PYQTFKDDPL RVLRLIRFAS RLGYRIDEET
EKAMQNSDIS EALRLKISKE RVCTELEKML RGPDPRGALH FIDRLQLYPT IFANHQDDVG
VDTSSWSLAY NSLQKILHPP KDSGEIAAVI ERVRSLLIRD SPETYYAWII AAFAPWSTVP
GRLPKPAAKA KPLPPRTAEV ARDSLRADNK TIVILKCASI NASSIIDTKS SLLENRLGGT
AAEIRQQIGL LIISWNKDWR LCVLLCILQE IMNGGEFSKV IQDYDSFLSY IITNNLEGVC
EMRPIVNGDE IMQTLGARKG PWMGKALDMV VKWQLLHPEI TEKEKALEEV AARECLQRTE
ESHALQDSLL GDITIPDALE PLWQDIISKG TTNNQETCES LLVAQGYLKV WGSRELSNED
ENAANSLYDW AKVKDSRLRS ILAVSALASL AALLPIRKAS NTPDIVIALA SFTYEKDPWT
TQKSLELSNQ LLEEFSKETK DDELWTFVER ILKERVRPLF SKTKNPAITA AGRKNFHPVP
LPRFDPSILN PESKPWKIHD VYATTVFGWV ISQYRSTDRQ HLETHFPLLV PVILTLIDDE
SLAFKARGCS ILSQFLTPIR ESKSDILRRT NLSSVFEDAI RPCLLSLPTI TPEDESIQLL
QVAYPALLSL LKTSYQTSTQ ENVKKSSTTD REAFISGVTK ILRDNLIPSF HHISSTNPTA
TSSYASFPHP RLSTLLVDEI CIILGELGIH TTKYLQEIIP PIYSTLSNPF GTAYTPLLLS
AVSATRAVIL NAHPRLWRWR GEILGGLCTC WLQILDEESE IAKRATRGRS SESDQSTGEA
MVRLKTELKG AVYLLKFALQ NPVQAEDDPG QLDAQENIKK ELQELVNADD TLGDLLLADI
DPNDPGYFGV GS
//
