ID A0A1L9RWJ5_ASPWE Unreviewed; 1171 AA.
AC A0A1L9RWJ5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN ORFNames=ASPWEDRAFT_49272 {ECO:0000313|EMBL:OJJ39237.1};
OS Aspergillus wentii DTO 134E9.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Cremei.
OX NCBI_TaxID=1073089 {ECO:0000313|EMBL:OJJ39237.1, ECO:0000313|Proteomes:UP000184383};
RN [1] {ECO:0000313|Proteomes:UP000184383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DTO 134E9 {ECO:0000313|Proteomes:UP000184383};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
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DR EMBL; KV878210; OJJ39237.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9RWJ5; -.
DR STRING; 1073089.A0A1L9RWJ5; -.
DR VEuPathDB; FungiDB:ASPWEDRAFT_49272; -.
DR OrthoDB; 142354at2759; -.
DR Proteomes; UP000184383; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR CDD; cd05510; Bromo_SPT7_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR006565; BTP.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037782; Spt7.
DR PANTHER; PTHR47343; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR PANTHER; PTHR47343:SF1; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR Pfam; PF07524; Bromo_TP; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000184383}.
FT DOMAIN 341..411
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1019..1171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..152
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1106..1162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1171 AA; 127330 MW; 77BB2EEB7D3CF26A CRC64;
MSLGHHHAWL PPGHLRPPDD PNDLRSVNGY SKSFSGPKTP QMRASVGADG PHAGNLISEA
DTAAEEDPRI AMFRDLYKCS EAKINYLFSK DPAAETPTST AVADAGESET QDARADQPAP
LPVPPKKPAR KLDDDDYDDY DEDEDDDDAE AADLAPSPVK AKPLMSSQDP SGIPSPSHRP
SVAPTDSSKE VKKETLEDIR KKLEEDKKAT EEAAKRSFHT IFYTLENDRD AMLDQQRLEE
SERQVEAEMS GQPNGGSNNA TSGSDGYGSL SSANLGASSL TLKNLIARID MKRTMVQASD
AELRSLMSEV RKNRSKWASE DKVGQEELYE AAEKVLSELK AMTEHSTAFL TRVNKRDAPD
YYTIIKHPMD LGTMTKKLKA LQYRSKQDFV DDLILIWSNC LKYNTNPEHF LRKHALYMKK
ETEKLVPLIP EIVIRDRAEV EAEERRLQMA ELDGAEESDD EPIMSSRGRK APGKSSKKGT
APVRNTPSGS EPPGAPASQP SAPVRSDSDV AMEGTQNGFA TPPPGIPTPS DPLGTGSGLP
GSHGDSMEID GMMSSSNALS ALSAAGTEVE DPEYKVWKQV TKKDRAVIAA ERHRLLKGDK
LNSDEPALLR TKAGMRRWLR NQKLNADIEK ARESTSQAMG PDAAGETLAE GIEEEEDKVI
PDYYDVMSGV PDLPEQILWR EDPDGNVVDA SEEFLRILPK GSFTQADSKL SRKMDANMQQ
MQETRKICSK VGIVKQMQLQ SQMYQNQFQK YQPEPFVEHD VPPHVMNDGG PVVSPWVCKA
AMQRSVAKIF YHAGFEEYQP SALDSVTDIA SDFFQKIGET LKSYMETPKA PTTDSPDNMS
SKSQWKRAYT EPEMVLHTLS SVGTDIESLE SYIKDDVDRL GTKLATVHDR LKSLLAELLR
PALADAGEDG SNAFADGSEQ FVGGDFAEDI DEDFFGFKEL GLDKEFGLAT LSVPLHLLQN
RLLNPSNAQN TSASPTVTLF TQPSAYPRIS VDTVSSQIGL MQGFFNQKLQ SNNNEPLVED
LELPPKQRPT ATRPRLPASG KIAPPAGLGS TTSPQKRPPP SGAPGQPGKS GPSEPSKKKV
KKNSGVSMGV PGSAAEGEES MDTKPMENPA LTNLKANDTN ADEGSAVSTT EMSSGKSGAD
STAPTSASNA DQNKTNEGAA PMTNGTLGDA S
//
