ID   A0A1L9RY81_ASPWE        Unreviewed;       688 AA.
AC   A0A1L9RY81;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Glutaminase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ASPWEDRAFT_49741 {ECO:0000313|EMBL:OJJ39889.1};
OS   Aspergillus wentii DTO 134E9.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Cremei.
OX   NCBI_TaxID=1073089 {ECO:0000313|EMBL:OJJ39889.1, ECO:0000313|Proteomes:UP000184383};
RN   [1] {ECO:0000313|Proteomes:UP000184383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DTO 134E9 {ECO:0000313|Proteomes:UP000184383};
RX   PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA   de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA   Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA   Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA   Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA   Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA   Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA   Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA   Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA   Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA   Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA   Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA   Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA   Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA   Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA   Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA   Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA   van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA   Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA   Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA   Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA   Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT   "Comparative genomics reveals high biological diversity and specific
RT   adaptations in the industrially and medically important fungal genus
RT   Aspergillus.";
RL   Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KV878210; OJJ39889.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1L9RY81; -.
DR   STRING; 1073089.A0A1L9RY81; -.
DR   VEuPathDB; FungiDB:ASPWEDRAFT_49741; -.
DR   OrthoDB; 3715424at2759; -.
DR   Proteomes; UP000184383; Unassembled WGS sequence.
DR   InterPro; IPR032515; DUF4964.
DR   InterPro; IPR014870; GtaA_C.
DR   InterPro; IPR032514; GtaA_central.
DR   InterPro; IPR033433; GtaA_N.
DR   PANTHER; PTHR31987; GLUTAMINASE A-RELATED; 1.
DR   PANTHER; PTHR31987:SF14; PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09910)-RELATED; 1.
DR   Pfam; PF08760; DUF1793; 1.
DR   Pfam; PF16334; DUF4964; 1.
DR   Pfam; PF16335; DUF4965; 1.
DR   Pfam; PF17168; DUF5127; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000184383};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..688
FT                   /note="Glutaminase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012137631"
FT   DOMAIN          29..88
FT                   /note="DUF4964"
FT                   /evidence="ECO:0000259|Pfam:PF16334"
FT   DOMAIN          108..327
FT                   /note="Glutaminase A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17168"
FT   DOMAIN          333..507
FT                   /note="Glutaminase A central"
FT                   /evidence="ECO:0000259|Pfam:PF16335"
FT   DOMAIN          508..677
FT                   /note="Glutaminase A C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08760"
SQ   SEQUENCE   688 AA;  74486 MW;  1E10B230C9008E29 CRC64;
     MGFFSNLRSA FGLILGSTLL HTSIAATFTP FAAPSYPLAV RNPYLSVWLP GDSASDLPSS
     SPKFWSGGDL TWSVIARVDG QAYNLFGVSS SLDNSKAATV TGASFTSTHS TFTLEAGSRT
     FTLDFLSPVS PKNLLRQSLP FAYLTISVSG ASDGSSVQIY SDIDSSWTGQ PDNSKWHITT
     NDTTSIYHLG PVNGATFSQT DPGQALWGET AYATRPSNQS NLTSASGPLS SIRSQFVSNG
     ALSNSHAEWT SDGVAGFAHD LGKVTDKTSV TFAIGHVRER VIDYVGNAQA GYYWAKYPGT
     VQVASHFLDD YAGAASESTA LDNLIQTGGE DAYGSNYSGI LALSLRQVFG GIEVTIPHDS
     LDTSNPSAFI KEISSNGNIN TVDVIYATFP IFYILSPEFI KLLIKPVLEY VTSDAYSEEY
     AVHDLGTHYP NATGHDPNGE AMPIEESGNI ILLTYAYEKG LGQSDISSNY GSLLQQYAQY
     LQNNGLYPAS QLSLNDALGE VANQTNLAVK AASALGAYGD LTSQTNYTNL GKEFADKIWT
     DRLGTDADGT YFTFQYGNDT WFETFNHYPD VLFNLDIFPQ EVYNATSAFY PTVRQAGGVA
     LKQDLNWGQT NWQSFVGATV TGEARDQYVA DLHAYISNGL NPAPFSDRYW VADNGEYKAG
     EYYVFRARPT LGSHFALWAL KGANQWSD
//